Effect of migration on risk of diabetes
| ISRCTN | ISRCTN38634580 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN38634580 |
| Secondary identifying numbers | Diabetes FUUTA |
- Submission date
- 13/01/2014
- Registration date
- 06/02/2014
- Last edited
- 06/02/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Nutritional, Metabolic, Endocrine
Plain English summary of protocol
Background and study aims
Type 2 diabetes is an increasing problem in sub-Saharian Africa: the prevalence and burden are rising very quickly as a consequence of major changes in lifestyle. In 2009 the International Diabetes Federation projected a 98% growth in the number of diabetic adults in this region. The main cause of diabetes in Africa, as everywhere, is impaired glucose tolerance (IGT), when blood glucose is raised beyond the normal range but it is not so high that you have diabetes. It is a consequence of urbanization and changes in diet. In Senegal (West Africa) it is already a great public health problem in the main city (Dakar) and its suburbs. In the villages, with a very different way of life, it is still unknown. In our hospital in Saint-Die (France) we have found that the Senegalese migrants (in majority coming from Fuuta, the northern region along the Senegal river) have a very high prevalence of IGT or type 2 diabetes. The aim of this study was to compare the prevalence of abnormal glucose status between the Senegalese migrants in France, especially around Saint-Die, and their relatives living in their villages in Fuuta. Our objective is to find out whether migration can lead to an increase of prevalence of IGT or type 2 diabetes among Senegalese migrants.
Who can participate?
We studied adults of both sexes, older than 18 years, who had accepted to be tested. The study involved two different populations. First, a study was conducted in Senegalese migrants in Saint-Die (SD group). Second, we studied the adult population of five villages in Fuuta (F group).
What does the study involve?
For all the selected participants we recorded the sex and age and measured height, weight, body mass index (BMI), waist/hip ratio and blood sugar levels.
What are the possible benefits and risks of participating?
There were no risks for the subjects. If we discovered a participant had type 2 diabetes the participant was informed of this so they could be treated.
Where is the study run from?
Centre Hospitalier Saint-Charles à Saint-Dié-des-Vosges (France).
When is the study starting and how long is it expected to run for?
The study began in November 2000 and finished in November 2001.
Who is funding the study?
Association pour la Prévention de lObésité et du Diabète en Déodatie (APODD) (Saint-Die, France).
Who in the main contact?
Dr JM Dollet
jean-marc-dollet@wanadoo.fr
Contact information
Scientific
Service de Médecine A
Centre Hospitalier Saint-Charles
Saint-Dié-des-Vosges
88100
France
| Phone | +33 (0) 608423941 |
|---|---|
| jean-marc-dollet@wanadoo.fr |
Study information
| Study design | Observational cohort study |
|---|---|
| Primary study design | Observational |
| Secondary study design | Cohort study |
| Study setting(s) | Hospital |
| Study type | Screening |
| Participant information sheet | Not available in web format, please use the contact details below to request a patient information sheet |
| Scientific title | High frequency of abnormal glucose tolerance in Senegalese migrants: a new example of the heavy consequences of the nutritional transition |
| Study acronym | Diabetes SD/F |
| Study objectives | Senegalese migrants have a higher risk of developing diabetes mellitus than their relatives remaining in their birth country. The main reason seems to be the nutritional transition (diet and sedentarity). We compared the prevalence of abnormal glucose status between Senegalese migrants and their relatives staying in their villages in Fuuta (a region in the Northern part of Senegal). |
| Ethics approval(s) | Ethics Commitee of Centre Hospitalier Saint-Charles à Saint-Dié-des-Vosges, June 2000 |
| Health condition(s) or problem(s) studied | Diabetes, migration, public health |
| Intervention | Study on Senegalese adults living in Saint-Die (France) and a representative sample of their relatives in five villages in Fuuta (Senegal). For all the selected subjects we measured four anthropometric parameters (height, weight, BMI and waist/hip ratio) and fasting capillary glycaemia. We stay for one day in each village. |
| Intervention type | Other |
| Primary outcome measure | 1. Anthropometric measures (height, weight, BMI and waist/hip ratio) 2. Blood capillary glucose, measured using a Glucotrend device (Lab. Boehringer) All of the measures were taken at baseline in one day. |
| Secondary outcome measures | N/A |
| Overall study start date | 01/11/2000 |
| Completion date | 01/11/2001 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | Both |
| Target number of participants | 50 in Saint-Die (France); 1000 in Fuuta (Senegal) |
| Key inclusion criteria | 1. All Senegalese migrants living in Saint-Die (France) 2. A representative sample of their relatives in five villages in Fuuta (Senegal) 3. Adults between 18 and 75 years |
| Key exclusion criteria | 1. Pregnancy 2. Illness |
| Date of first enrolment | 01/11/2000 |
| Date of final enrolment | 01/11/2001 |
Locations
Countries of recruitment
- France
- Senegal
Study participating centre
88100
France
Sponsor information
Hospital/treatment centre
c/o Dr Jean-Marc Dollet
Service de Médecine A
Centre Hospitalier Saint-Charles
Saint-Dié-des-Vosges
88100
France
| Website | http://www.centrehospitalierdesaintdiedesvosges.com/ |
|---|---|
"ROR" |
https://ror.org/000tm9s39 |
Funders
Funder type
Hospital/treatment centre
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
