The influence of prolonged prone position ventilation in patients of acute respiratory distress syndrome (ARDS) due to severe community-acquired pneumonia

ISRCTN	ISRCTN46247055
DOI	https://doi.org/10.1186/ISRCTN46247055
Protocol serial number	IRBTCVGH910911
Sponsor	Taichung Veterans General Hospital (Taiwan)
Funder	Taichung Veterans General Hospital (Taiwan)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr Chieh-Liang Wu
Scientific

No. 160, Sec. 3, Chung-Kang Rd.
Taichung
40705
Taiwan

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	To test if prolonged prone position ventilation can improve oxygenation in patients with severe community-acquired pneumonia. We also evaluate the associated complications due to this maneuver and plasma cytokine level change.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Severe community-acquired pneumonia with ARDS
Intervention	Continuous prone position ventilation for 72 hours versus supine position
Intervention type	Other
Primary outcome measure(s)	1. Improvement of oxygenation 2. Complications associated with prolonged position ventilation
Key secondary outcome measure(s)	1. Plasma cytokine levels 2. Mortality
Completion date	31/12/2003

Participant type(s)	Patient
Age group	Adult
Sex	All
Target sample size at registration	30
Key inclusion criteria	Severe community-acquired pneumonia with ARDS
Key exclusion criteria	Home oxygen use needed, pulmonary tuberculosis, malignancy under chemotherapy, acquired immunodeficiency syndrome (AIDS), organ transplant or autoimmune disease under immunosuppressant therapy, bone fracture and spine instability.
Date of first enrolment	01/09/2002
Date of final enrolment	31/12/2003

No. 160, Sec. 3, Chung-Kang Rd.

Taichung
40705
Taiwan

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/09/2007		Yes	No