The influence of prolonged prone position ventilation in patients of acute respiratory distress syndrome (ARDS) due to severe community-acquired pneumonia
| ISRCTN | ISRCTN46247055 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN46247055 |
| Secondary identifying numbers | IRBTCVGH910911 |
- Submission date
- 13/06/2005
- Registration date
- 14/06/2005
- Last edited
- 30/10/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Chieh-Liang Wu
Scientific
Scientific
No. 160, Sec. 3, Chung-Kang Rd.
Taichung
40705
Taiwan
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | To test if prolonged prone position ventilation can improve oxygenation in patients with severe community-acquired pneumonia. We also evaluate the associated complications due to this maneuver and plasma cytokine level change. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Severe community-acquired pneumonia with ARDS |
| Intervention | Continuous prone position ventilation for 72 hours versus supine position |
| Intervention type | Other |
| Primary outcome measure | 1. Improvement of oxygenation 2. Complications associated with prolonged position ventilation |
| Secondary outcome measures | 1. Plasma cytokine levels 2. Mortality |
| Overall study start date | 01/09/2002 |
| Completion date | 31/12/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target number of participants | 15 prone and 15 supine |
| Key inclusion criteria | Severe community-acquired pneumonia with ARDS |
| Key exclusion criteria | Home oxygen use needed, pulmonary tuberculosis, malignancy under chemotherapy, acquired immunodeficiency syndrome (AIDS), organ transplant or autoimmune disease under immunosuppressant therapy, bone fracture and spine instability. |
| Date of first enrolment | 01/09/2002 |
| Date of final enrolment | 31/12/2003 |
Locations
Countries of recruitment
- Taiwan
Study participating centre
No. 160, Sec. 3, Chung-Kang Rd.
Taichung
40705
Taiwan
40705
Taiwan
Sponsor information
Taichung Veterans General Hospital (Taiwan)
Hospital/treatment centre
Hospital/treatment centre
No. 160, Sec. 3, Chung-Kang Rd.
Taichung
407
Taiwan
| Website | http://www.vghtc.gov.tw |
|---|---|
"ROR" |
https://ror.org/00e87hq62 |
Funders
Funder type
Hospital/treatment centre
Taichung Veterans General Hospital (Taiwan)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/09/2007 | Yes | No |
