Medical Research Council Trial of Immediate versus Deferred Treatment for Intracerebral Brain Tumours Presenting With Epilepsy

ISRCTN	ISRCTN46552426
DOI	https://doi.org/10.1186/ISRCTN46552426
Secondary identifying numbers	BR08

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Dr - -
Scientific

UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Not Specified
Scientific title	Medical Research Council Trial of Immediate versus Deferred Treatment for Intracerebral Brain Tumours Presenting With Epilepsy
Study objectives	Not provided at time of registration
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Brain and Nervous System
Intervention	1. Group A: Immediate treatment with clinicians choice of one or more of surgery, radiotherapy or chemotherapy, plus best medical treatment 2. Group B: Deferred treatment, with best medical treatment only until intervention becomes clinically necessary
Intervention type	Other
Primary outcome measure	Not provided at time of registration
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/12/1988
Completion date	10/12/1993
Reason abandoned (if study stopped)	Participant recruitment issue

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	Not provided at time of registration
Key inclusion criteria	1. Patients with a clinically definite history of epilepsy who have Computed Tomography (CT) and/or Magnetic Resonance (MR) imaging supporting a probable diagnosis of intracerebral tumour 2. Clinical picture, CT or MR imaging is unequivocal and allows exclusion of cerebral abscess or extra-axial tumour (meningioma) 3. No other medical condition likely to effect the feasibility of follow-up 4. No previous neurosurgery, radiotherapy or chemotherapy 5. No other previous or concurrent malignant disease, except non melanomatous carcinoma of the skin 6. Age >16
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/12/1988
Date of final enrolment	10/12/1993

UKCCCR Register Co-ordinator

London
NW1 2DA
United Kingdom

Medical Research Council (MRC) (UK)
Research council

20 Park Crescent
London
W1B 1AL
United Kingdom

Phone	+44 (0)20 7636 5422
Email	clinical.trial@headoffice.mrc.ac.uk
Website	http://www.mrc.ac.uk

Government

Medical Research Council (UK)
Government organisation / National government

Alternative name(s): Medical Research Council (United Kingdom), UK Medical Research Council, MRC
Location: United Kingdom

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

15/11/2019: Study stopped due to poor recruitment.
21/01/2019: No publications found. All search options exhausted.