Effect of rapid transcranial magnetic stimulation (rTMS) on subjective responses to methamphetamine in healthy subjects
| ISRCTN | ISRCTN46614315 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN46614315 |
| Protocol serial number | N/A |
| Sponsor | Medical Research Council (MRC) (UK) |
| Funder | Medical Research Council (UK) |
- Submission date
- 06/04/2000
- Registration date
- 06/04/2000
- Last edited
- 03/05/2011
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr PJ Cowen
Scientific
Scientific
University Department of Psychiatry
University of Oxford
Warneford Hospital
Old Road
Headington
Oxford
OX4 4XN
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | The purpose of this study is to test the hypothesis that repetitive Transcranial Magnetic Stimulation (rTMS) can attenuate the behavioural response to amphetamine in healthy volunteers. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Neurosciences, psychiatry |
| Intervention | rTMS versus sham application (placebo). Both groups receive methamphetamine. |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Methamphetamine |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/03/2000 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 24 |
| Key inclusion criteria | 1. No significant current or past psychiatric disorder or substance misuse 2. No current physical illness |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/03/1999 |
| Date of final enrolment | 01/03/2000 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
University Department of Psychiatry
Oxford
OX4 4XN
United Kingdom
OX4 4XN
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/12/2000 | Yes | No |
