Impact of nursing checklist management on treatment timeliness and neurological function recovery in patients undergoing interventional surgery for acute ischemic stroke
| ISRCTN | ISRCTN47973264 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN47973264 |
| Sponsor | The Central Hospital of Xiangtan |
| Funders | Hunan Provincial Health Commission National Key Clinical Specialty Major Project, Xiangtan City Medical Research Project, Hunan Provincial Natural Science Foundation Project, Chinese Nursing Association Project, Hunan Provincial Health Commission Project, Hunan Provincial People's Hospital Medical Alliance Project |
- Submission date
- 21/01/2026
- Registration date
- 21/01/2026
- Last edited
- 21/01/2026
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Plain English summary of protocol
Background and study aims
Current research on the application of checklist management in nursing for Acute Ischemic Stroke interventional surgery is limited both domestically and internationally, with most studies being observational or involving small samples, and lacking high-quality randomized controlled trial evidence. This study aims to construct a nursing checklist suitable for AIS interventional surgery through a rigorous randomized controlled trial design and to verify its application effect.
Who can participate?
Patients who underwent interventional therapy for acute ischemic stroke aged 18-90 years
What does the study involve?
This study employs a prospective randomized controlled trial design to construct and verify the application effect of a standardized nursing checklist in Acute Ischemic Stroke interventional surgery, evaluate its impact on treatment timeliness and neurological function recovery, and provide evidence-based support for establishing a standardized Acute Ischemic Stroke interventional nursing model.
What are the possible benefits and risks of participating?
The application of nursing checklist management in interventional surgery for acute ischemic stroke may shorten the treatment time, significantly promote the recovery of neurological function, and reduce the risk of complications.
There is no risk in participating in this study.
Where is the study run from?
The Central Hospital of Xiangtan (China)
When is the study starting and how long is it expected to run for?
From January 2024 to March 2025
Who is funding the study?
Hunan Provincial Health Commission National Key Clinical Specialty Major Project, Project Number: Z2023138;
Xiangtan City Medical Research Project, Project Number: 2023-xtyx-23;
Hunan Provincial Natural Science Foundation Project, Project Number: 2024JJ9561;
Chinese Nursing Association Project, Project Number: ZHKY202406;
Hunan Provincial Health Commission Project, Project Number: 202114010862;
Hunan Provincial People's Hospital Medical Alliance Project, Project Number: 2023YLT002
Who is the main contact?
Dr Fangqun Cheng
The Central Hospital of Xiangtan
chengfq_2025@126.com
Contact information
Principal investigator, Scientific, Public
No. 120, Heping Road, Yuhu District
Xiangtan
411100
China
| Phone | +86 73158214885 |
|---|---|
| chengfq_2025@126.com |
Study information
| Primary study design | Interventional |
|---|---|
| Allocation | Randomized controlled trial |
| Masking | Blinded (masking used) |
| Control | Active |
| Assignment | Single |
| Purpose | Supportive care |
| Scientific title | A quantitative study on the impact of nursing checklist management on treatment timeliness and neurological function recovery in patients undergoing interventional surgery for acute ischemic stroke |
| Study objectives | |
| Ethics approval(s) |
Approved 04/06/2024, Ethics Committee of The Central Hospital of Xiangtan (No. 120, Heping Road, Yuhu District, Xiangtan, 411100, China; +86 731 58214988; xtchllwyh@163.com), ref: 2024-06-002 |
| Health condition(s) or problem(s) studied | Treatment timeliness and neurological function recovery in patients undergoing interventional surgery for acute ischemic stroke |
| Intervention | A computer-generated random number table method is used to randomly assign patients to the observation group and control group. 1. Intervention Methods for the Observation Group Assemble an expert team to develop a Nursing Checklist for Interventional Procedures in Acute Ischemic Stroke. The observation group is managed using an interventional surgery checklist based on the standardized routine nursing model. The nursing checklist for interventional surgery for acute ischemic stroke includes 7 dimensions:preoperative assessment, preoperative preparation, intraoperative monitoring, intraoperative cooperation, postoperative management, transfer and handover, and disposal and disinfection 7, with a total of 27 items, distributed in 3 stages:preoperative, intraoperative, and postoperative 3. Among them, preoperative assessment 6 items;preoperative preparation 4 items;intraoperative monitoring 2 items;intraoperative cooperation 6 items;postoperative management 4 items;transfer and handover 2 items;disposal and disinfection 3 items. 2. Control Group Intervention Protocol The control group received routine care according to the"Perioperative Nursing Expert Consensus for Endovascular Interventional Therapy in Patients with Acute Ischemic Stroke". This included nurses collaborating with physicians to complete initial assessment and management of the patient's condition after admission, completing various preoperative examinations, as well as routine preparation, cooperation, and nursing for the surgery, and postoperative monitoring of vital signs and observation for complications, but without the use of structured checklist tools. |
| Intervention type | Other |
| Primary outcome measure(s) |
|
| Key secondary outcome measure(s) | |
| Completion date | 28/03/2025 |
Eligibility
| Participant type(s) | |
|---|---|
| Age group | Mixed |
| Lower age limit | 18 Years |
| Upper age limit | 90 Years |
| Sex | All |
| Target sample size at registration | 142 |
| Total final enrolment | 142 |
| Key inclusion criteria | 1. Aged 18-90 years 2. Time from onset to consultation≤24 hours 3. Diagnosed with acute ischemic stroke by clinical symptoms, signs, and imaging examinations such as head CT and MRI 4. National Institutes of Health Stroke Scale (NIHSS)score≥6 points 5. Imaging confirms large vessel occlusion 6. Signed informed consent |
| Key exclusion criteria | 1. Concomitant severe heart, liver, or kidney dysfunction (NYHA class IV heart function, Child-Pugh class C liver function, chronic kidney disease 5) 2. Advanced malignant tumor 3. MMSE score<24 points 4. Severe residual deficits from previous stroke (mRS>3points) 5. Pregnancy or lactation 6. Participation in other clinical trials |
| Date of first enrolment | 08/01/2024 |
| Date of final enrolment | 25/10/2024 |
Locations
Countries of recruitment
- China
Study participating centres
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|
Editorial Notes
21/01/2026: Trial's existence confirmed by Ethics Committee of The Central Hospital of Xiangtan.
