A prospective randomised trial of resection versus biopsy in patients with malignant glioma

ISRCTN	ISRCTN48935548
DOI	https://doi.org/10.1186/ISRCTN48935548
Protocol serial number	E164/45
Sponsor	Medical Research Council (MRC) (UK)
Funder	Medical Research Council (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Miss Sally Stenning
Scientific

MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom

Email	ss@ctu.mrc.ac.uk

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study acronym	-
Study objectives	This trial will compare two treatments - radiotherapy or chemotherapy (using temozolomide) in patients for whom it is decided active treatment is needed. Patients entered onto the trial will be randomly selected to one of the two treatments available.
Ethics approval(s)	Not provided at time of registration.
Health condition(s) or problem(s) studied	Cancer
Intervention	Trial stopped: Not submitted for funding
Intervention type	Drug
Phase	Phase III
Drug / device / biological / vaccine name(s)	Temozolomide
Primary outcome measure(s)	Not provided at time of registration.
Key secondary outcome measure(s)	Not provided at time of registration.
Completion date	01/09/2005
Reason abandoned (if study stopped)	Lack of funding

Participant type(s)	Patient
Age group	Adult
Sex	All
Key inclusion criteria	Not provided at time of registration.
Key exclusion criteria	Not provided at time of registration.
Date of first enrolment	01/09/1999
Date of final enrolment	01/09/2005

MRC Clinical Trials Unit

London
NW1 2DA
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan