A comparison between the use of transurethral resection of the prostate (TURP) with bipolar cutting loop diathermy for the treatment of benign prostatic hypertrophy

ISRCTN	ISRCTN49628875
DOI	https://doi.org/10.1186/ISRCTN49628875
Protocol serial number	N0234156276
Sponsor	Department of Health
Funder	North Bristol NHS Trust (UK), NHS R&D Support Funding

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Mr Matthew Goh
Scientific

BUI
Southmead Hospital
Bristol
BS16 1ND
United Kingdom

Primary study design	Interventional
Study design	Prospective randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	Effects of standard TURP using 5% glycine as irrigation with bipolar resection which can use normal saline as irrigation fluid.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Urological and Genital Diseases: Benign prostatic hyperplasia (BPH)
Intervention	Randomised to either bipolar resection with normal saline or TURP with glycine
Intervention type	Other
Primary outcome measure(s)	ECG evidence of ischaemia, chest pain, cardiac arrhythmias, neurological symptoms, biochemistry results, haematology research
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	01/12/2006

Participant type(s)	Patient
Age group	Not Specified
Sex	Male
Target sample size at registration	210
Key inclusion criteria	All patients scheduled for TURP under spinal anaesthesia will be approached.
Key exclusion criteria	Inability to give informed consent, general anaesthesia
Date of first enrolment	01/12/2004
Date of final enrolment	01/12/2006

BUI

Bristol
BS16 1ND
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan