Attentional style in bipolar disorder
| ISRCTN | ISRCTN50788919 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN50788919 |
| Secondary identifying numbers | 5864 |
- Submission date
- 12/05/2010
- Registration date
- 12/05/2010
- Last edited
- 11/08/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Catherine Harmer
Scientific
Scientific
University Department of Psychiatry
Warneford Lane
Headington
Oxford
OX3 7JX
United Kingdom
Study information
| Study design | Single-centre interventional treatment trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | 1. Do patients with bipolar disorder display an attentional bias towards threat? 2. Can this bias be modified using a simple computer-based intervention? 3. Does modifying the bias lead to changes in the emotional response to stressful situations? |
| Ethics approval(s) | MREC approved, ref: 08/H0603/36 |
| Health condition(s) or problem(s) studied | Topic: Mental Health Research Network; Subtopic: Bipolar affective disorder; Disease: Bipolar affective disorder |
| Intervention | Intervention - positive attention training: this involves completing a computer-based task on the day of testing. The task requires that particiapnts pay less attention to negative information. Participants complete the task only during the testing session. The task takes approximately 30 minutes to complete. Control - neutral attention training: this is identical to the intervention task except that the participants are not required to direct their attention away from negative information. Study entry: registration and one or more randomisations. |
| Intervention type | Other |
| Primary outcome measure | Attentional bias as measured using a computerised task (the dot-probe task) on the day of testing |
| Secondary outcome measures | 1. Symptoms of anxiety, measured on a 10-point scale and collected via SMS messaging three times a day for the week following testing 2. Symptoms of low mood (measured using the Positive Affect Negative Affect Schedule [PANAS] scale) and anxiety (measured using the State-Trait Anxiety Inventory [STAI] scale) immediately following testing |
| Overall study start date | 13/03/2009 |
| Completion date | 01/10/2011 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | Planned sample size: 80; UK sample size: 80 |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 13/03/2009 |
| Date of final enrolment | 01/10/2011 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
University Department of Psychiatry
Oxford
OX3 7JX
United Kingdom
OX3 7JX
United Kingdom
Sponsor information
University of Oxford (UK)
University/education
University/education
Research Services
Clinical Trials and Research Governance
Headley Way
Headington
Oxford
OX3 9DU
England
United Kingdom
| Website | http://www.ox.ac.uk/ |
|---|---|
"ROR" |
https://ror.org/052gg0110 |
Funders
Funder type
Charity
The Wellcome Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
