The effect of targeted exercise on falls and function for people with Parkinson's disease (Group Exercise Trial for Parkinson's disease - GET uP study)

ISRCTN	ISRCTN50793425
DOI	https://doi.org/10.1186/ISRCTN50793425
Protocol serial number	RDA/02/06/041
Sponsor	Peninsula Medical School (UK)
Funder	Personal Award Scheme Researcher Development Award from National Institute of Health Research (UK) Ref: RDA/02/06/041

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Mrs Victoria Goodwin
Scientific

Primary Care Research Group
Peninsula Medical School
Smeall Building
St Luke's Campus
Exeter
EX1 2LU
United Kingdom

Phone	+44 (0)1392 262745
Email	victoria.goodwin@pms.ac.uk

Primary study design	Interventional
Study design	Randomised, single-blind, controlled trial.
Secondary study design	Randomised controlled trial
Scientific title
Study acronym	Acronym added as of 28/06/2007: GET uP
Study objectives	What is the effectiveness of a targeted exercise programme on reducing falls and improving the physical function of people with Parkinson's disease who have a history of falling?
Ethics approval(s)	Devon and Torbay Research Ethics Committee, approved on 5 February 2007. Ref: 07/Q2102/8
Health condition(s) or problem(s) studied	Parkinson's disease
Intervention	A group based strength and balance exercise progamme, led by a physiotherapist plus additional home exercises versus usual care for 10 weeks.
Intervention type	Other
Primary outcome measure(s)	Falls at 10 and 30 weeks post baseline/recruitment.
Key secondary outcome measure(s)	1. Balance (Berg Balance scale) 2. Mobility (Timed Up and Go test) 3. Fear of falling (Falls efficacy scale - international) 4. Physical self-perception (physical self-perception profile) 5. Habitual physical activity, assessed using the "Phone - FITT" tool ("FITT" stands for Frequency, Intensity, Time, and Type of activity) 6. Quality of life (EQ-5D)
Completion date	30/04/2009

Participant type(s)	Patient
Age group	Not Specified
Sex	All
Target sample size at registration	248
Key inclusion criteria	People diagnosed with Parkinson's disease who report two or more falls in the past year and who are independently mobile.
Key exclusion criteria	1. Needs supervision or assistance from another person to mobilise indoors 2. Significant comorbidity or symptoms that would affect ability or safety to participate in group exercise 3. Inability to follow written and verbal instructions in English
Date of first enrolment	12/03/2007
Date of final enrolment	30/04/2009

Primary Care Research Group

Exeter
EX1 2LU
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/11/2011		Yes	No