The effect of probiotic therapy on nosocomial infections in the critically ill
| ISRCTN | ISRCTN51777318 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN51777318 |
| Protocol serial number | N0192133923 |
| Sponsor | Department of Health |
| Funder | Nottingham University Hospitals NHS Trust (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 18/10/2017
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr D Knight
Scientific
Scientific
Department of Anaesthesia and Intensive Care
Queens Medical Centre
University Hospital
Nottingham
NG7 2UH
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | The effect of probiotic therapy on nosocomial infections in the critically ill |
| Study objectives | Does early enteral feeding with probiotics reduce the rate of nosocomial (hospital acquired) infections in the critically ill? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Infections and Infestations: Nosocomial infections |
| Intervention | 1. Lactobacillus 2. Placebo |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Probiotics |
| Primary outcome measure(s) |
Oropharyngeal nosocomial bacterial carriage rates, nosocomial infection rates, death rates, diarrhoea rates. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 31/12/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | All |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 07/10/2003 |
| Date of final enrolment | 31/12/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Department of Anaesthesia and Intensive Care
Nottingham
NG7 2UH
United Kingdom
NG7 2UH
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
18/10/2017: No publications found, study status unverified
