Post-operative levonorgestrel-releasing intra uterine system (IUS) treatment after conservative surgery for symptomatic endometriosis stage I to IV to reduce pelvic pain symptoms

ISRCTN	ISRCTN51782640
DOI	https://doi.org/10.1186/ISRCTN51782640
Protocol serial number	N0256159399
Sponsor	Department of Health
Funder	The Royal Free Hampstead NHS Trust (UK) NHS R&D Support Funding

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Dr Adam L Magos
Scientific

University Department Of Obstetrics and Gynaecology
Royal Free Hampstead NHS Trust
Pond Street
Hampstead
London
NW3 2QG
United Kingdom

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	Post-operative levonorgestrel-releasing intra uterine system (IUS) treatment after conservative surgery for symptomatic endometriosis stage I to IV to reduce pelvic pain symptoms
Study objectives	Can we reduce the recurrence of pelvic pain after conservative surgical treatment by inserting the IUS at the time of surgery?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Urological and Genital Diseases: Pelvic pain
Intervention	Randomised Clinical Trial
Intervention type	Other
Primary outcome measure(s)	Reduction in severity of dysmenorrhoea, pelvic pain and deep dyspareunia as assessed by multidimensional analogue questionnaire between the group treated with levonogestrel-IUS and controls
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	31/12/2004

Participant type(s)	Patient
Age group	Adult
Sex	Female
Target sample size at registration	80
Key inclusion criteria	40 patients and 40 controls
Key exclusion criteria	Does not match inclusion criteria
Date of first enrolment	01/01/2002
Date of final enrolment	31/12/2004

University Department Of Obstetrics and Gynaecology

London
NW3 2QG
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes

18/10/2017: No publications found in PubMed, verifying study status with principal investigator.