Does an intensive development procedure of multidisciplinary guidelines improve prescribing behaviour: a pre/post study with concurrent control group and a randomised subgroup
| ISRCTN | ISRCTN53308138 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN53308138 |
| Protocol serial number | N/A |
| Sponsor | Care and Public Health Research Institute (CAPHRI) (Netherlands) |
| Funder | The two local insurance companies (VGZ and CZ) provided funding sources for this study (Netherlands). |
- Submission date
- 20/09/2005
- Registration date
- 28/09/2005
- Last edited
- 10/09/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Other
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Johan L. Severens
Scientific
Scientific
Department of Health Organisation, Policy and Economics
P.O. Box 616
Maastricht
6200 MD
Netherlands
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Two hypotheses: 1. Dissemination of locally and multidisciplinairy developed guidelines can lead to a modest but relevant change of volumes of prescriptions in the desired direction 2. What is the additional effect on change of volumes of prescriptions because of involving the target group in the preparation and development of the guidelines |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Improving rational prescribing behaviour among GPs in the Netherlands |
| Intervention | The randomised intervention concerns the intensified involvement of GPs in the development procedure of a set of prescription guidelines. A randomised subgroup of GPs were invited for a more intense role and received conceptual guidelines to comment on them. The other GPs only received the final version of the prescription guidelines. The second design of our study, the quasi experiment, concerns the dissemination of locally and multidisciplinary guidelines in the south of the Netherlands, controlled by a comparable region elsewhere in the Netherlands. The guidelines contained 14 recommendations on antibiotics, asthma/COPD drugs and cholesterol drugs. |
| Intervention type | Other |
| Primary outcome measure(s) |
Prescription data, gathered retrospectively per GP per month during the period 2001-2004. Expected directions of change have been defined based on the detailed recommendations contained in the guidelines, in combination with estimates based on the expertise of the initially involved key regional representatives. |
| Key secondary outcome measure(s) |
Drug volumes and pre/post changes between groups on short-term and long term (one and two years after). |
| Completion date | 01/02/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 53 |
| Key inclusion criteria | Completeness of the GPs data (no missing data per GP for more than one year) and at least 500 patients in the GPs practice |
| Key exclusion criteria | GPs outside the region |
| Date of first enrolment | 01/02/2001 |
| Date of final enrolment | 01/02/2004 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Department of Health Organisation, Policy and Economics
Maastricht
6200 MD
Netherlands
6200 MD
Netherlands
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 02/11/2006 | Yes | No |
