Randomised trial of neo-adjuvant therapy in patients with stage IIIA non small cell lung cancer
| ISRCTN | ISRCTN54157750 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN54157750 |
| Protocol serial number | LU20 |
| Sponsor | Medical Research Council (MRC) (UK) |
| Funder | Medical Research Council (MRC) (UK) |
- Submission date
- 28/02/2001
- Registration date
- 28/02/2001
- Last edited
- 20/02/2020
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Danielle Andrews
Scientific
Scientific
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom
| abc@123.com |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | - |
| Study objectives | To compare in patients with stage IIIA non small cell lung cancer a policy of standard therapy with thoracic radiotherapy versus a policy of chemotherapy followed, if feasible, by surgery |
| Ethics approval(s) | Not provided at time of registration. |
| Health condition(s) or problem(s) studied | Cancer |
| Intervention | 1. One group receives standard therapy with thoracic radiotherapy 2. The other group receives chemotherapy followed, if feasible, by surgery |
| Intervention type | Other |
| Primary outcome measure(s) |
1. Survival time |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/05/1999 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | All |
| Target sample size at registration | 350 |
| Total final enrolment | 48 |
| Key inclusion criteria | 1. No previous treatment for the current lung cancer 2. Either sex 3. World Health Organisation (WHO) 0-2, T3N1M0 or T1-3N2M0 stage |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/09/1995 |
| Date of final enrolment | 01/05/1999 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
MRC Clinical Trials Unit
London
NW1 2DA
United Kingdom
NW1 2DA
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/09/2005 | 20/02/2020 | Yes | No |
| Study website | Study website | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
20/02/2020: The following changes have been made:
1. Publication reference added.
2. The total final enrolment number has been added from the reference.
3. The trial website was added.
