Randomised study of Early Assessment by CT scanning in Trauma patients
| ISRCTN | ISRCTN55332315 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN55332315 |
| Protocol serial number | ZON-MW 3920.0005 |
| Sponsor | Academic Medical Center (AMC) (The Netherlands) |
| Funder | The Netherlands Organization for Health Research and Development (Zon-Mw) (Netherlands) |
- Submission date
- 12/09/2005
- Registration date
- 12/09/2005
- Last edited
- 02/05/2012
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Injury, Occupational Diseases, Poisoning
Plain English summary of protocol
Not provided at time of registration
Contact information
Scientific
Trauma Unit AMC, G4-105
Postbus 22660
Amsterdam
1100 DD
Netherlands
| Phone | +31 (0)20 5666019 |
|---|---|
| j.c.goslings@amc.uva.nl |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | |
| Study acronym | REACT Trial |
| Study objectives | A trauma care strategy involving early shockroom CT scanning with a standard diagnostic imaging strategy in trauma patients has a positive effect on both patient outcome and operations research. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Trauma |
| Intervention | Patients are transported to either the VUmc or the AMC, based on randomisation. Trauma care will remain the same for both institutions, with the only difference the location of the CT scanner. |
| Intervention type | Other |
| Primary outcome measure(s) |
The number of days spent outside the hospital in the first year following the emergency admission in the shockroom will be our primary outcome. This outcome is responsive to differences in mortality (no more/additional days outside hospital), to differences in hospital stay for the initial admission, to differences in readmission rate (i.e. because of missed diagnoses). Furthermore, there is a positive association between a shorter hospital stay and better functional health. Care will be given to harmonize discharge criteria between the two hospitals. |
| Key secondary outcome measure(s) |
The secondary outcome parameters for the patient outcome part of the study will focus on: |
| Completion date | 01/05/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 1124 |
| Key inclusion criteria | All patients that are transported to the AMC or VUmc shockroom according to current pre-hospital triage system based on: 1. Injury mechanism 2. Revised Trauma Score 3. Presence or absence of traumatic brain injury |
| Key exclusion criteria | Excluded from analysis and comparison are: 1. Patients younger than 16 years of age 2. Death during transport to the hospital |
| Date of first enrolment | 01/11/2005 |
| Date of final enrolment | 01/05/2007 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
1100 DD
Netherlands
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/01/2012 | Yes | No | |
| Protocol article | 1. study protocol | 22/08/2008 | Yes | No | |
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
| Study website | Study website | 11/11/2025 | 11/11/2025 | No | Yes |