Illumination in human aging: sleep and mood effects
| ISRCTN | ISRCTN55452501 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN55452501 |
| Secondary identifying numbers | 5 RO1 AG12364-11A1 |
- Submission date
- 06/05/2005
- Registration date
- 11/05/2005
- Last edited
- 14/02/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Daniel Kripke
Scientific
Scientific
9500 Gillman Drive
La Jolla, CA
92093-0667
United States of America
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study acronym | LRX |
| Study objectives | Bright white light would reduce depression and improve sleep disorders related to circadian rhythm disturbance. |
| Ethics approval(s) | The study protocol and consent form were approved by the University of California and San Diego (UCSD) Human Research Protection Program. |
| Health condition(s) or problem(s) studied | Depression and disturbed sleep |
| Intervention | One hour bright white light compared to one hour dim red light at three different times of day. |
| Intervention type | Other |
| Primary outcome measure | 1. Mood scales 2. Light recording 3. Wrist actigraphy 4. Assays of urine for aMT6s 5. Assays of saliva for melatonin |
| Secondary outcome measures | No secondary outcome measures |
| Overall study start date | 01/04/2000 |
| Completion date | 31/01/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Senior |
| Sex | All |
| Target number of participants | 81 |
| Key inclusion criteria | 1. Humans aged 60 - 79 years 2. No history of mania 3. No diagnosis of bipolar disorder |
| Key exclusion criteria | Lifetime history of mania. |
| Date of first enrolment | 01/04/2000 |
| Date of final enrolment | 31/01/2004 |
Locations
Countries of recruitment
- United States of America
Study participating centre
9500 Gillman Drive
La Jolla, CA
92093-0667
United States of America
92093-0667
United States of America
Sponsor information
National Institutes of Health (NIH)/National Institute of Aging (NIA) (USA)
Government
Government
7201 Wisconsin Ave.
Bethesda, MD
20892
United States of America
| Website | http://www.nia.nih.gov/ |
|---|---|
"ROR" |
https://ror.org/049v75w11 |
Funders
Funder type
Government
National Institutes of Health (NIH)/National Institute of Aging (NIA) (USA) (ref: 5 RO1 AG12364-11A1)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 09/11/2005 | Yes | No |
