Effect of increased intra-operative inspired oxygen concentration on the prevention of postoperative nausea and vomiting in paediatric tonsillectomy
| ISRCTN | ISRCTN55885217 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN55885217 |
| Protocol serial number | N0212115628 |
| Sponsor | Department of Health (UK) |
| Funder | Royal United Hospital NHS Trust (UK) |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 16/06/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr A Mayor
Scientific
Scientific
Department of Anaesthesia
Royal United Hospital
B&NES
Bath
BA1 3NG
United Kingdom
| Phone | +44 (0)1225 825057 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | |
| Study objectives | To investigate whether the relatively simple manoeuvre of increasing inspired oxygen from 30-80% during anaesthesia shows a reduction in post-operative nausea and vomiting in children post adenotonsillectomy. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Signs and Symptoms: Vomiting |
| Intervention | Increasing inspired oxygen vs standard practice |
| Intervention type | Other |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/06/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Child |
| Upper age limit | 15 Years |
| Sex | All |
| Key inclusion criteria | Patients aged <15 years undergoing adenotonsillectomy at RUH operating theatres |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/09/2002 |
| Date of final enrolment | 01/06/2003 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Department of Anaesthesia
Bath
BA1 3NG
United Kingdom
BA1 3NG
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
