Proton pump inhibitor (PPI) treatment of gastro-oesophageal reflux (GOR) associated with non-cardiac chest pain (NCCP)
| ISRCTN | ISRCTN56363424 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN56363424 |
| Protocol serial number | N0123138371 |
| Sponsor | Department of Health |
| Funder | University Hospitals of Leicester NHS Trust (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 28/07/2017
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Digestive System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Peter Wurm
Scientific
Scientific
University Hospitals of Leicester
c/o Research and Development Office
Leicester General Hospital NHS Trust
Leicester
LE1 4PW
United Kingdom
| Phone | +44 (0)116 258 4109 |
|---|---|
| nicola.turner@uhl-tr.nhs.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | Proton pump inhibitor (PPI) treatment of gastro-oesophageal reflux (GOR) associated with non-cardiac chest pain (NCCP) |
| Study objectives | 1. To investigate the efficacy of a proton pump inhibitor (PPI) (omeprazole 40 mg) of non-cardiac chest pain (NCCP) in patients with pH-metric evidence of abnormal gastro-oesophageal reflux (GOR) 2. To clarify which factor - endoscopic oesophagitis, positive symptom index, positive acid perfusion test - best identifies patients |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Gastro-oesophageal reflux disease (GORD) |
| Intervention | Randomised controlled trial |
| Intervention type | Other |
| Primary outcome measure(s) |
Proton pump inhibitor treatment of gastro-oesophageal reflux (GOR) associated with non cardiac chest pain (NCCP) |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/04/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Patients associated with non cardiac chest pain |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/08/2002 |
| Date of final enrolment | 01/04/2003 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
University Hospitals of Leicester
Leicester
LE1 4PW
United Kingdom
LE1 4PW
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/07/2010 | Yes | No |
Editorial Notes
28/07/2017: Publication reference added.
