Proton pump inhibitor (PPI) treatment of gastro-oesophageal reflux (GOR) associated with non-cardiac chest pain (NCCP)
| ISRCTN | ISRCTN56363424 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN56363424 |
| Secondary identifying numbers | N0123138371 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 28/07/2017
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Digestive System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English Summary
Not provided at time of registration
Contact information
Dr Peter Wurm
Scientific
Scientific
University Hospitals of Leicester
c/o Research and Development Office
Leicester General Hospital NHS Trust
Leicester
LE1 4PW
United Kingdom
| Phone | +44 (0)116 258 4109 |
|---|---|
| nicola.turner@uhl-tr.nhs.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | Proton pump inhibitor (PPI) treatment of gastro-oesophageal reflux (GOR) associated with non-cardiac chest pain (NCCP) |
| Study hypothesis | 1. To investigate the efficacy of a proton pump inhibitor (PPI) (omeprazole 40 mg) of non-cardiac chest pain (NCCP) in patients with pH-metric evidence of abnormal gastro-oesophageal reflux (GOR) 2. To clarify which factor - endoscopic oesophagitis, positive symptom index, positive acid perfusion test - best identifies patients |
| Ethics approval(s) | Not provided at time of registration |
| Condition | Gastro-oesophageal reflux disease (GORD) |
| Intervention | Randomised controlled trial |
| Intervention type | Other |
| Primary outcome measure | Proton pump inhibitor treatment of gastro-oesophageal reflux (GOR) associated with non cardiac chest pain (NCCP) |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/08/2002 |
| Overall study end date | 01/04/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | Not provided at time of registration |
| Participant inclusion criteria | Patients associated with non cardiac chest pain |
| Participant exclusion criteria | Not provided at time of registration |
| Recruitment start date | 01/08/2002 |
| Recruitment end date | 01/04/2003 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
University Hospitals of Leicester
Leicester
LE1 4PW
United Kingdom
LE1 4PW
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Government
University Hospitals of Leicester NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/07/2010 | Yes | No |
Editorial Notes
28/07/2017: Publication reference added.
