Treatment of borderline hypertension by light - moderate, lifestyle exercise
| ISRCTN | ISRCTN56552651 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN56552651 |
| Protocol serial number | C/PHI/04/15-06-94/RIDDOCH/D |
| Sponsor | NHS R&D Regional Programme Register - Department of Health (UK) |
| Funder | NHS Executive South West (UK) |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 15/12/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Chris Riddoch
Scientific
Scientific
University of Bristol
Department of Sport, Exercise and Health Science
University of Bristol
34 West Park
Bristol
BS8 2LU
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Current guidelines for the management of hypertension recommend regular, moderate intensity aerobic exercise such as brisk walking as a means of blood pressure reduction. However, there is a lack of consistent evidence regarding the magnitude of blood pressure response to such a prescription. In particular, no well designed studies have investigated the efficacy of a programme of exercise meeting current guidelines. AIM: To investigate the effect of a six-week programme of moderate intensity exercise on daytime ambulatory blood pressure (10.00 am to 10.00 pm) among unmedicated, sedentary adults aged 25 years to 63 years with office blood pressure of 150 mmHg to 180 mmHg systolic and/or 91 mmHg to 110 mmHg diastolic. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular diseases: Hypertension |
| Intervention | 1. 30 minutes of moderate intensity exercise (brisk walking or equivalent) five days per week for six weeks 2. Maintenance of existing levels of physical activity |
| Intervention type | Other |
| Primary outcome measure(s) |
Blood pressure |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 31/12/1997 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | Not Specified |
| Key inclusion criteria | Sedentary adults aged 25 to 63 years with office blood pressure of 150 mmHg to 180 mmHg systolic and/or 91 mmHg to 110 mmHg diastolic |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/06/1995 |
| Date of final enrolment | 31/12/1997 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
University of Bristol
Bristol
BS8 2LU
United Kingdom
BS8 2LU
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/12/2000 | Yes | No |
