Cardiopulmonary resuscitation (CPR) quality improvement programme

ISRCTN	ISRCTN56583860
DOI	https://doi.org/10.1186/ISRCTN56583860
Protocol serial number	PB-PG-1207-14246
Sponsor	Heart of England NHS Foundation Trust (UK)
Funder	National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme (PB-PG-1207-14246)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Prof Gavin Perkins
Scientific

Warwick Medical School Clinical Trials Unit
University of Warwick
Coventry
CV4 7AL
United Kingdom

Email	g.d.perkins@warwick.ac.uk

Primary study design	Interventional
Study design	Multicentre prospective cohort study
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	Cardiopulmonary resuscitation (CPR) quality improvement programme: a multicentre, prospective, cohort study
Study objectives	Implementing a CPR quality improvement initiative will improve the rate of return of spontaneous circulation and other outcomes in patients sustaining cardiac arrest
Ethics approval(s)	Coventry Research Ethics Committee, 26/06/2009, REC ref: 09/H1210/65
Health condition(s) or problem(s) studied	In-hospital cardiac arrests
Intervention	1. Control 2. CPR feedback through Q-CPR® (Laerdal medical, UK) 3. CPR feedback through Q-CPR® (Laerdal medical, UK) plus team briefing / debriefing
Intervention type	Other
Primary outcome measure(s)	Survived event [defined as sustained (> 20 minutes) return of spontaneous circulation]
Key secondary outcome measure(s)	1. Patient outcomes 1.1. Any return of spontaneous circulation 1.2. Survival to hospital discharge 1.3. Cerebral performance category of patients at discharge 2. Process outcomes 2.1. Quality of emergency calls 2.2. Chest compression depth, rate 2.3. No flow time 2.4. Duration of pre and post-shock pauses 2.5. Ventilation rate 2.6. time to first shock 2.7.Appropriate decision to shock 3. Team factors 3.1. CPR knowledge 3.2. Confidence / preparedness
Completion date	31/01/2013

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	All
Target sample size at registration	912
Key inclusion criteria	Patients have to be either 18 or older and suffer an in-hospital cardiac arrest where resuscitation is attempted (defined as loss of a pulse requiring the delivery of chest compressions).
Key exclusion criteria	1. Patient has a Do-not-attempt resuscitation order written and documented in their medical records 2. Cardiac arrest not attended by a resuscitation team 3. Out - of - hospital cardiac arrest 4. Previous participation in this study
Date of first enrolment	01/11/2009
Date of final enrolment	31/01/2013

Warwick Medical School Clinical Trials Unit

Coventry
CV4 7AL
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/11/2015		Yes	No
Protocol article	protocol	18/10/2011		Yes	No
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes

04/02/2016: Publication reference added.