The effect of pharmacological agents on uterine junctional zone contractions during mock embryo transfer: a randomised double-blind study
| ISRCTN | ISRCTN57835722 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN57835722 |
| Protocol serial number | N0084096582 |
| Sponsor | Department of Health |
| Funder | The North and South Bank Research and Development Consortium (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 31/03/2020
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Pregnancy and Childbirth
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Frank Biervliet
Scientific
Scientific
Academic Department of Obstetrics & Gynaecology
Hull & East Yorkshire (NHS) Trust
The Princess Royal Hospital
Salthouse Road
Hull
HU8 9HE
United Kingdom
| Phone | +44 (0)1482 701151 |
|---|---|
| abc@email.com |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised double-blind study |
| Secondary study design | Randomised controlled trial |
| Scientific title | The effect of pharmacological agents on uterine junctional zone contractions during mock embryo transfer: a randomised double-blind study |
| Study objectives | To assess if junctional zone contractions can be reduced by pharmacological agents. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Pregnancy and Childbirth: Embryo transfer |
| Intervention | The patient's baseline junctional zone contractions will be established following a 5 minute scan. Video tapes taken of both the pre and post mock embryo transfer will be assessed by two researchers who will be unaware of treatment. 20 patients allocated to the nitric oxide group, 20 to the non-steroidal anti-inflammatory group, 20 control and 20 to the COX-2 inhibitor group. |
| Intervention type | Drug |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | |
| Primary outcome measure(s) |
1. Number of contractions per unit time |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 10/12/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target sample size at registration | 80 |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/04/2000 |
| Date of final enrolment | 10/12/2003 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
The Princess Royal Hospital
Hull
HU8 9HE
United Kingdom
HU8 9HE
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
31/03/2020: No publications found, all search options exhausted, study status unverified.
