Acupuncture for treatment of knee osteoarthritis: immunological view
| ISRCTN | ISRCTN59953486 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN59953486 |
| Secondary identifying numbers | 21161 |
- Submission date
- 09/03/2005
- Registration date
- 07/11/2006
- Last edited
- 23/09/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Musculoskeletal Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof M Fathy ElBatouty
Scientific
Scientific
Mansoura University Hospitals
Mansoura
11135
Egypt
| amalfehr@yahoo.com |
Study information
| Study design | Randomised three armed prospective study |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | Acupuncture for treatment of knee osteoarthritis: immunological view |
| Study acronym | APOA-Eg |
| Study objectives | Effect of acupuncture on markers of knee OsteoArthritis (OA) in Egyptians. |
| Ethics approval(s) | Rheumatology and Physical Medicine Department, Faculty of medicine, Mansoura University (Egypt). |
| Health condition(s) or problem(s) studied | Knee osteoarthritis (OA) |
| Intervention | Two groups receive verum (real) acupuncture either with manual manipulation, or with electro-acupuncture, and the third sham (control) acupuncture. |
| Intervention type | Other |
| Primary outcome measure | Western Ontario and McMaster Universities Arthritis Index (WOMAC) scale |
| Secondary outcome measures | Immunological study for adhesion molecules such as intercellular adhesion molecule 1 (ICAM1) and cytokines such as interleukin-1beta (IL1B) and Tumor Necrosis Factor (TNF) alpha, before and after treatment. |
| Overall study start date | 01/06/2005 |
| Completion date | 01/06/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 300 patients with knee OA |
| Key inclusion criteria | Patients are included if they: 1. Agreed to participate in the study by written, informed consent 2. Fulfilled the American College of Rheumatology criteria for knee OA |
| Key exclusion criteria | 1. Non-compliance 2. High serum uric acid |
| Date of first enrolment | 01/06/2005 |
| Date of final enrolment | 01/06/2007 |
Locations
Countries of recruitment
- Egypt
Study participating centre
Mansoura University Hospitals
Mansoura
11135
Egypt
11135
Egypt
Sponsor information
Mansoura University Hospital (Egypt)
Hospital/treatment centre
Hospital/treatment centre
Elgomhoria Street
Mansoura Faculty of Medicine
Mansoura
35516
Egypt
| Phone | +20 502247055 |
|---|---|
| mua@mans.edu.eg | |
| Website | http://www.mans.eun.eg/english/ |
"ROR" |
https://ror.org/00c8rjz37 |
Funders
Funder type
Other
Investigator funded trial - no external funding was gained for this trial.
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
23/09/2021: Proactive update review. No publications found. Search options exhausted.
