Perioperative anxiety: a comparison between diazepam and propranolol
| ISRCTN | ISRCTN60630970 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN60630970 |
| Secondary identifying numbers | N0280123688 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 11/07/2016
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr B Hedayati
Scientific
Scientific
Anaesthetics
Arrowe Park Hospital
Arrowe Park Road
Upton
Wirral
CH49 5PE
United Kingdom
| Phone | +44 (0)151 604 7056 |
|---|---|
| babak.hedayati@btconnect.com |
Study information
| Study design | Prospective randomised double-blind controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | Perioperative anxiety: a comparison between diazepam and propranolol |
| Study objectives | Both drugs are anxiolytic, but propranolol should not cause cognitive/psychomotor dysfunction postoperatively, possibly allowing earlier patient discharge |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Mental and Behavioural Disorders: Perioperative anxiety |
| Intervention | Patients undergoing surgery will be randomised to receive 1. Diazepam 2. Propranolol |
| Intervention type | Other |
| Primary outcome measure | 1. Preoperative anxiety - Hospital Anxiety and Depression Score (HADS) and Visual Analogue Scale (VAS) 2. Pulse/blood pressure - postoperatively 3. VAS - postoperative nausea, vomiting, pain, sedation and satisfaction 4. Tests of cognitive/psychomotor dysfunction - postoperative |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/08/2003 |
| Completion date | 31/07/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Both |
| Target number of participants | 80 |
| Key inclusion criteria | 80 inpatients |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 01/08/2003 |
| Date of final enrolment | 31/07/2004 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Anaesthetics
Wirral
CH49 5PE
United Kingdom
CH49 5PE
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Hospital/treatment centre
Wirral Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
11/07/2016: No publications found, study status unverified
