Evaluation of equivalent effective dose of ephedrine and phenylephrine in prevention of hypotension after spinal anaesthesia for caesarean section
| ISRCTN | ISRCTN62049497 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN62049497 |
| Protocol serial number | N0436130343 |
| Sponsor | Department of Health |
| Funder | Leeds Teaching Hospitals NHS Trust |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 17/11/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Pregnancy and Childbirth
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr S Saravanan
Scientific
Scientific
Obstetric Anaesthesia Office
Gledhow Wing
Leeds Teaching Hospitals NHS Trust
Beckett Street
Leeds
LS9 7TF
United Kingdom
| Phone | +44 (0)113 243 3144 |
|---|---|
| r&d@leedsth.nhs.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | The aim of this study is to determine whether ephedrine or phenylephrine or a combination provides the best prophylactic for prevention of hypotension after spinal anaesthesia |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Pregnancy and Childbirth: Anaesthesia |
| Intervention | Randomised controlled trial to determine whether ephedrine or phenylephrine or a combination provides the best prophylactic for prevention of hypotension after spinal anaesthesia. |
| Intervention type | Other |
| Primary outcome measure(s) |
Efficacy in preventing cardiovascular instability |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/07/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Key inclusion criteria | Women who have completed 36 weeks of normal pregnancy, fit and well normally and who are planned to have an elective caesarean section under spinal anaesthesia will be recruited |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2003 |
| Date of final enrolment | 01/07/2003 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Obstetric Anaesthesia Office
Leeds
LS9 7TF
United Kingdom
LS9 7TF
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/01/2006 | Yes | No |
