Randomised controlled trial of Dihydrocodeine (DHC) and methadone in the treatment of opiate dependent patients
| ISRCTN | ISRCTN63574530 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN63574530 |
| Protocol serial number | K/OPR/2/2/D399 |
| Sponsor | Chief Scientist Office (UK) - Scottish Executive Health Department |
| Funder | Chief Scientist Office (UK) - Scottish Executive Health Department |
- Submission date
- 08/03/2005
- Registration date
- 20/04/2005
- Last edited
- 18/09/2007
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Roy Robertson
Scientific
Scientific
Muirhouse Medical Group
1 Muirhouse Avenue
Edinburgh
EH4 4PL
United Kingdom
| Phone | +44 (0)131 537 4343 |
|---|---|
| Roy.Robertson@ed.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | To determine the efficacy of dihdrocodeine compared to methadone in the treatment of opiate dependence. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Opiate dependence |
| Intervention | Substitute treatment with methadone or dihydrocodeine. |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Dihydrocodeine (DHC), methadone |
| Primary outcome measure(s) |
1. Survival |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/03/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 250 |
| Key inclusion criteria | Opiate dependent patients |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/09/2000 |
| Date of final enrolment | 01/03/2005 |
Locations
Countries of recruitment
- United Kingdom
- Scotland
Study participating centre
Muirhouse Medical Group
Edinburgh
EH4 4PL
United Kingdom
EH4 4PL
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 01/12/2006 | Yes | No | |
| Study website | Study website | 11/11/2025 | 11/11/2025 | No | Yes |
