Randomised controlled trial of Dihydrocodeine (DHC) and methadone in the treatment of opiate dependent patients
| ISRCTN | ISRCTN63574530 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN63574530 |
| Secondary identifying numbers | K/OPR/2/2/D399 |
- Submission date
- 08/03/2005
- Registration date
- 20/04/2005
- Last edited
- 18/09/2007
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Roy Robertson
Scientific
Scientific
Muirhouse Medical Group
1 Muirhouse Avenue
Edinburgh
EH4 4PL
United Kingdom
| Phone | +44 (0)131 537 4343 |
|---|---|
| Roy.Robertson@ed.ac.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | |
| Study objectives | To determine the efficacy of dihdrocodeine compared to methadone in the treatment of opiate dependence. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Opiate dependence |
| Intervention | Substitute treatment with methadone or dihydrocodeine. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Dihydrocodeine (DHC), methadone |
| Primary outcome measure | 1. Survival 2. Retention in treatment 3. Continued drug use (particularly injecting) 4. Criminal behaviour |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/09/2000 |
| Completion date | 01/03/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 250 |
| Key inclusion criteria | Opiate dependent patients |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/09/2000 |
| Date of final enrolment | 01/03/2005 |
Locations
Countries of recruitment
- Scotland
- United Kingdom
Study participating centre
Muirhouse Medical Group
Edinburgh
EH4 4PL
United Kingdom
EH4 4PL
United Kingdom
Sponsor information
Chief Scientist Office (UK) - Scottish Executive Health Department
Government
Government
St Andrew's House
Regent Road
Edinburgh
EH1 3DG
United Kingdom
| Phone | +44 (0)131 244 2077 |
|---|---|
| Peter.craig@scotland.gsi.gov.uk | |
| Website | http://www.sehd.scot.nhs.uk/cso/ |
"ROR" |
https://ror.org/01bw7zm61 |
Funders
Funder type
Government
Chief Scientist Office (UK) - Scottish Executive Health Department
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 01/12/2006 | Yes | No |
