Ward oriented pharmacy In Newly admitted Geriatric Seniors (WINGS)

ISRCTN	ISRCTN64974377
DOI	https://doi.org/10.1186/ISRCTN64974377
Secondary identifying numbers	N/A

Submission date: 22/12/2010
Registration date: 07/02/2011
Last edited: 20/06/2022

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Injury, Occupational Diseases, Poisoning

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Loraine Lie-A-Huen
Scientific

Department of Hospital Pharmacy
Meibergdreef 9
Amsterdam
1105AZ
Netherlands

Phone	+31 (0)20 566 9111
Email	L.LieaHuen@amc.nl

Dr Joanna Klopotowska
Scientific

Amsterdam University Medical Centre
Room # J1B-115-2
Meibergdreef 15
Amsterdam
1105 AZ
Netherlands

Phone	+31 06-14393672
Email	j.e.klopotowska@amsterdamumc.nl

Study information

Study design	Multicentre interrupted time series study
Primary study design	Interventional
Secondary study design	Multi-centre
Study setting(s)	Hospital
Study type	Quality of life
Scientific title	The effect of an active on-ward participation of hospital pharmacists in internal medicine teams on preventable adverse drug events in elderly in-patients
Study acronym	WINGS Study
Study objectives	To investigate whether an active participation of hospital pharmacists in a care team on the ward can be an effective approach in reducing prescribing errors and related patient harm in elderly in-patients admitted to Internal Medicine ward.
Ethics approval(s)	Before the start of this study, the research protocol was submitted for consideration to the Medical Ethics Committee of the Academic Medical Center/University of Amsterdam. This Medical Ethics Committee judged the protocol as not needing an official approval. This decision was sent in a letter by Medical Ethics Committee, dated 14th February 2007 (ref: 0717.0176). In this letter the Medical Ethics Committe states that for the above mentioned scientific project, the Dutch Medical Research involving Human Subjects Act (WMO) does not apply. This means that an official approval of the study by our committee is not required.
Health condition(s) or problem(s) studied	Adverse drug events
Intervention	"Ward Oriented Pharmacy", a concept based on Clinical Pharmacy practice, will be developed and introduced to Internal Medicine wards. "Ward Oriented Pharmacy" entails an active participation of hospital pharmacists in care teams by implementing a multidisciplinary medication-safety program for elderly in-patients. In the WINGS study an interrupted time series design is used. Before and after the introduction of the intervention on the Internal Medicine wards, a pre- and post- measurement was performed. Per measurement three data points were strategically chosen (a total of six data points). Every data point had at least 50 patients included. The data for the pre-measurement were collected between April 2007 and November 2007. The data for the post-measurement were collected between November 2009 and June 2010. If an included patient was readmitted or died within 3 months after index hospitalisation (hospitalisation included in the study), this outcome was recorder in a WINGS database.
Intervention type	Other
Primary outcome measure	1. The incidence, severity, type, preventability and follow-up of ADEs in elderly in-patients 2. The number of all and preventable ADEs per 100 admissions of elderly in-patients admitted to an Internal Medicine ward
Secondary outcome measures	1. The number of selected medication errors per total number of medication orders 2. The number of readmissions within 3 months after index admission
Overall study start date	01/03/2007
Completion date	01/03/2010

Eligibility

Participant type(s)	Patient
Age group	Senior
Sex	Both
Target number of participants	500
Total final enrolment	250
Key inclusion criteria	1. Participating hospitals are: Academic Medical Centre in Amsterdam, Westfries Gasthuis Hospital in Hoorn, Spaarne Hospital in Hoofddorp, the Netherlands 2. All consecutive patients aged 65 years or older 3. Length of stay of 24 hours or longer 4. Using 5 or more scheduled medications 5. Admitted to a internal medicine ward of the participating hospitals during observation points No patient will be sampled more than once.
Key exclusion criteria	1. Admitted for scheduled chemotherapy, radiation therapy or transplantation 2. Transferred from another hospital or from another non-internal medicine ward within the hospital
Date of first enrolment	01/03/2007
Date of final enrolment	01/03/2010

Locations

Countries of recruitment

Netherlands

Study participating centre

Department of Hospital Pharmacy

Amsterdam
1105AZ
Netherlands

Sponsor information

The Netherlands Organization for Health Research and Development (ZonMw) (Netherlands)
Research organisation

Postbox 93 245
The Hague
2509 AE
Netherlands

Phone	+31 (0)70 349 51 11
Email	info@zonmw.nl
Website	http://www.zonmw.nl/nl/
"ROR"	https://ror.org/01yaj9a77

Funders

Funder type

Research organisation

The Netherlands Organization for Health Research and Development (ZonMw) (Netherlands)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan	Not provided at time of registration

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Protocol article	protocol	25/05/2011		Yes	No
Results article	results	01/01/2013		Yes	No
Results article		05/08/2013	13/05/2022	Yes	No
Results article		17/06/2022	20/06/2022	Yes	No

Editorial Notes

20/06/2022: Publication reference added.
13/05/2022: The following changes have been made:
1. Publication reference added.
2. The final enrolment number has been added from the reference.
3. A scientific contact has been added.