Pharmacological Treatment of Congenital Nystagmus

ISRCTN	ISRCTN65414827
DOI	https://doi.org/10.1186/ISRCTN65414827
Protocol serial number	N0123112717
Sponsor	University Hospitals Leicester (UK)
Funders	Nystagmus Network UK, Ulverscroft Foundation, University Hospitals of Leicester NHS Trust

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Prof Irene Gottlob
Scientific

University Hospitals of Leicester
c/o Research and Development Office
Leicester General Hospital NHS Trust
Leicester
LE1 4PW
United Kingdom

Primary study design	Interventional
Study design	Placebo controlled randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study acronym	PTCN
Study objectives	To investigate whether memantine and gabapentin improve nystagmus.
Ethics approval(s)	Leicestershire Ethics Committee
Health condition(s) or problem(s) studied	Nystagmus
Intervention	Administration of gabapentin, memantine or a placebo
Intervention type	Drug
Phase	Not Specified
Drug / device / biological / vaccine name(s)	Memantine and gabapentin
Primary outcome measure(s)	Visual acuity
Key secondary outcome measure(s)	Nystagmus amplitude
Completion date	01/03/2006

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	All
Target sample size at registration	48
Key inclusion criteria	1. Congenital nystagmus 2. Over 18 years of age
Key exclusion criteria	1. Other neurological condition 2. Pregnancy or breastfeeding 3. Unable or unwilling to give consent
Date of first enrolment	01/08/2004
Date of final enrolment	01/03/2006

University Hospitals of Leicester

Leicester
LE1 4PW
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	Results	01/02/2007		Yes	No