Automatic weaning with adaptive support ventilation (ASV): effect on nurse workload and duration of spontaneous ventilation until extubation
| ISRCTN | ISRCTN65935865 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN65935865 |
| Secondary identifying numbers | NTR154 |
- Submission date
- 20/12/2005
- Registration date
- 20/12/2005
- Last edited
- 03/11/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr M J Schultz
Scientific
Scientific
Department of Intensive Care
Academic Medical Centre
University of Amsterdam
Meibergdreef 9
Amsterdam
1105 AZ
Netherlands
| m.j.schultz@amc.uva.nl |
Study information
| Study design | Randomised, active controlled, parallel group trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | We hypothesise that: 1. Adaptive support ventilation (ASV) reduces the number of nurse-ventilator interactions in non-fast track cardiac surgery patients 2. ASV lengthens the period of spontaneous breathing, while shortening the total respiratory weaning time |
| Ethics approval(s) | Received from the local medical ethics committee |
| Health condition(s) or problem(s) studied | Mechanical ventilation |
| Intervention | Patients will be either ventilated in a standard fashion (i.e., pressure controlled mechanical ventilation or pressure support mechanical ventilation) or by ASV. |
| Intervention type | Other |
| Primary outcome measure | 1. Number of arterial blood gas (ABG) analyses 2. Number of audible alarms 3. Number of manual changes in the ventilator settings, including: 3.1. Switches from PC to PS (only in the control group) 3.2. Changes in minute ventilation (only in the ASV group) 3.3. Lowering of PS-level (only in the control group) 4. Duration of period of spontaneous mechanical ventilation 5. Duration of total period of tracheal intubation |
| Secondary outcome measures | No secondary outcome measures |
| Overall study start date | 01/10/2005 |
| Completion date | 01/10/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 128 |
| Key inclusion criteria | 1. Planned uneventful cardiac surgery i.e. coronary artery bypass graft (CABG) 2. Following receipt of verbal and written information about the trial, the patient must provide signed and dated informed consent before any trial related activity is carried out |
| Key exclusion criteria | 1. History of pulmonary disease 2. History of pulmonary surgery 3. Valve surgery 4. Arrival at the IC-unit with IABP or inotropes at a more then usual rate (in ml per hour: dopamine (4), norepinephrine (4), dobutamin (4) or epinephrine [any rate]) |
| Date of first enrolment | 01/10/2005 |
| Date of final enrolment | 01/10/2006 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Department of Intensive Care
Amsterdam
1105 AZ
Netherlands
1105 AZ
Netherlands
Sponsor information
Academic Medical Centre (AMC) (Netherlands)
Hospital/treatment centre
Hospital/treatment centre
Department of Obstetrics and Gynaecology
Meibergdreef 9
Amsterdam
1105 AZ
Netherlands
| Website | http://www.amc.uva.nl/ |
|---|---|
"ROR" |
https://ror.org/03t4gr691 |
Funders
Funder type
Not defined
Not provided at time of registration
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
