Randomised controlled trial of Skin Prick Testing

ISRCTN	ISRCTN66284870
DOI	https://doi.org/10.1186/ISRCTN66284870
Protocol serial number	06/039/SMI
Sponsor	Brighton and Sussex University Hospitals NHS Trust (UK)
Funders	Brighton and Sussex Medical School (UK) - originally held by from Southampton University, Alk-Abello Ltd (UK) (ref: D105 R107)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Prof Helen Smith
Scientific

Brighton and Sussex Medical School
Mayfield House
University of Brighton
Falmer
Brighton
BN1 9PH
United Kingdom

Phone	+44 (0)1273 644563
Email	h.e.smith@bsms.ac.uk

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title
Study acronym	SPT
Study objectives	Does allergy assessment and appropriate advice in general practice enhance the care of patients with asthma and rhinitis and is it cost effective compared with routine medical care?
Ethics approval(s)	Ethics approval received from the Multicentre Research Ethics Committee on the 26th May 2003 (ref: MREC/02/10/13).
Health condition(s) or problem(s) studied	Asthma and rhinitis
Intervention	Allergy intervention - structured allergy history and skin prick testing and appropriate advice on allergy avoidance versus routine medical care
Intervention type	Other
Primary outcome measure(s)	1. Symptom scores (validated scale for asthma and rhinoconjunctivitis) 2. Health-related quality of life (using child or adult specific instruments)
Key secondary outcome measure(s)	1. Patients' subjective assessment of symptomatic improvement 2. Change in patient management (introduction or withdrawal of allergen avoidance)
Completion date	01/05/2008

Participant type(s)	Patient
Age group	Adult
Sex	All
Target sample size at registration	528
Key inclusion criteria	Patients with a working diagnosis of asthma and/or rhinoconjunctivitis
Key exclusion criteria	1. Less than 5 years or greater than 50 years 2. Terminal illness 3. Confusional state 4. History of anaphylaxis 5. Tested in the preceding two years
Date of first enrolment	01/05/2006
Date of final enrolment	01/05/2008

Brighton and Sussex Medical School

Brighton
BN1 9PH
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/03/2009		Yes	No
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes