A randomised controlled trial of a home based, targeted progressive exercise programme aimed at improving endurance and function in adults with muscular dystrophy (MD).
| ISRCTN | ISRCTN67078621 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN67078621 |
| Protocol serial number | N0176140663 |
| Sponsor | Department of Health |
| Funders | Oxford Radcliffe Hospitals NHS Trust (UK), NHS R&D Support Funding |
- Submission date
- 30/09/2005
- Registration date
- 30/09/2005
- Last edited
- 03/07/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Musculoskeletal Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Helen Dawes
Scientific
Scientific
School of Biological & Molecular Sciences
Oxford Brookes University
Gypsy Lane Campus
Headington
Oxford
OX3 OB
United Kingdom
| Phone | +44 (0)1865 483293 |
|---|---|
| hdawes@brookes.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | The study sets out to examine the effect of a targeted aerobic exercise programme in adults with muscular dystrophy who are able to walk at least 10 metres but have some gait impairment. In adults with muscular dystrophy, will a targeted home based progressive exercise programme aimed at improving endurance: 1. Improve mobility (walking distance and speed) 2. Decrease fatigue 3. Improve muscle function (increase muscle strength, speed and power) 4. Improve aerobic fitness 5. Improve perceived performance in specifically targeted functional activities? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Musculoskeletal Diseases: Muscular dystrophy (MD) |
| Intervention | Home based exercise programme vs no home based exercise programme |
| Intervention type | Other |
| Primary outcome measure(s) |
Primary and secondary outcome measures 8 weeks following treatment intervention, and then after another 8 weeks. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/12/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target sample size at registration | 40 |
| Key inclusion criteria | Adults with Muscular Dystrophy of 16 years and above with some gait impairment and perceived reduced mobility and function that are able to walk at least 10m (aids permitted). Perceived mobility and perceived functional impairment of the lower limb. |
| Key exclusion criteria | Unable to meet the inclusion criteria or those unwilling or unable to undertake the programme |
| Date of first enrolment | 01/04/2004 |
| Date of final enrolment | 01/12/2004 |
Locations
Countries of recruitment
- United Kingdom
Study participating centre
School of Biological & Molecular Sciences
Oxford
OX3 OB
United Kingdom
OX3 OB
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/08/2006 | Yes | No |
