A randomised controlled trial of a home based, targeted progressive exercise programme aimed at improving endurance and function in adults with muscular dystrophy (MD).

ISRCTN ISRCTN67078621
DOI https://doi.org/10.1186/ISRCTN67078621
Secondary identifying numbers N0176140663
Submission date
30/09/2005
Registration date
30/09/2005
Last edited
03/07/2008
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Musculoskeletal Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Helen Dawes
Scientific

School of Biological & Molecular Sciences
Oxford Brookes University
Gypsy Lane Campus
Headington
Oxford
OX3 OB
United Kingdom

Phone +44 (0)1865 483293
Email hdawes@brookes.ac.uk

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Not specified
Study typeNot Specified
Scientific title
Study objectivesThe study sets out to examine the effect of a targeted aerobic exercise programme in adults with muscular dystrophy who are able to walk at least 10 metres but have some gait impairment. In adults with muscular dystrophy, will a targeted home based progressive exercise programme aimed at improving endurance:
1. Improve mobility (walking distance and speed)
2. Decrease fatigue
3. Improve muscle function (increase muscle strength, speed and power)
4. Improve aerobic fitness
5. Improve perceived performance in specifically targeted functional activities?
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedMusculoskeletal Diseases: Muscular dystrophy (MD)
InterventionHome based exercise programme vs no home based exercise programme
Intervention typeOther
Primary outcome measurePrimary and secondary outcome measures 8 weeks following treatment intervention, and then after another 8 weeks.
Secondary outcome measuresNot provided at time of registration
Overall study start date01/04/2004
Completion date01/12/2004

Eligibility

Participant type(s)Patient
Age groupAdult
SexNot Specified
Target number of participants20 patients, 20 control patients, total 40
Key inclusion criteriaAdults with Muscular Dystrophy of 16 years and above with some gait impairment and perceived reduced mobility and function that are able to walk at least 10m (aids permitted). Perceived mobility and perceived functional impairment of the lower limb.
Key exclusion criteriaUnable to meet the inclusion criteria or those unwilling or unable to undertake the programme
Date of first enrolment01/04/2004
Date of final enrolment01/12/2004

Locations

Countries of recruitment

  • United Kingdom

Study participating centre

School of Biological & Molecular Sciences
Oxford
OX3 OB
United Kingdom

Sponsor information

Department of Health
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Phone +44 (0)20 7307 2622
Email dhmail@doh.gsi.org.uk
Website http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Government

Oxford Radcliffe Hospitals NHS Trust (UK)

No information available

NHS R&D Support Funding

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/08/2006 Yes No