Mirror therapy in patients with complex regional pain syndrome type one of the upper extremity: a randomised clinical trial
| ISRCTN | ISRCTN68438240 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN68438240 |
| Protocol serial number | N/A |
| Sponsor | Erasmus Medical Centre (The Netherlands) |
| Funders | Erasmus Medical Centre (The Netherlands), Medical Research Advisory Committee Erasmus (MRACE) (The Netherlands) |
- Submission date
- 23/02/2007
- Registration date
- 23/02/2007
- Last edited
- 08/09/2011
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Musculoskeletal Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Ton A R Schreuders
Scientific
Scientific
Erasmus Medical Centre
Department of Rehabilitation Medicine, Room H014
P.O. Box 2040
Rotterdam
3000 CA
Netherlands
| Phone | +31 (0)10 463 2867 |
|---|---|
| a.schreuders@erasmusmc.nl |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised, active controlled, parallel group, single blinded trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Mirror therapy was introduced by Ramachandran in patient with phantom limb pain and is based on new knowledge about the plasticity of the brain. Recently, studies in patients with Complex Regional Pain Syndrome (CRPS) have suggested that exercising with the painful hand behind a mirror and watching a reflection of the normal hand will give the brain the illusion that the hand is now able to move normally. In these controlled but undersized studies, positive effects were reported on pain, oedema and hand function. In the present single-blind randomised clinical trial, mirror therapy will be presented in three phases: 1. One week Recognition of Hand Laterality using pictures of left and right hands 2. One week of Imagined Hand Movements, and 3. Four weeks of mirror therapy Hypothesis: Mirror therapy in patients with Complex Regional Pain Syndrome type one (CRPS I) has a positive effect on pain, oedema, sensibility, hand function, Activities of Daily Living (ADL) and quality of life compared to standard treatment. |
| Ethics approval(s) | Ethics approval received from the local medical ethics committee |
| Health condition(s) or problem(s) studied | Complex regional pain syndrome type 1 (CRPS I) |
| Intervention | Mirror therapy versus standard treatment: 1. One week recognition of hand laterality using pictures of left and right hands 2. One week of imagined hand movements, and 3. Four weeks of mirror therapy The control group will receive treatment following standard treatment guidelines. |
| Intervention type | Other |
| Primary outcome measure(s) |
Pain |
| Key secondary outcome measure(s) |
1. Hand function |
| Completion date | 01/12/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 52 |
| Key inclusion criteria | Modified research diagnostic criteria for CRPS-1 based on Bruehl 1999. |
| Key exclusion criteria | 1. Treatment for CRPS-I in another institution 2. Psychiatric problems 3. Lack of motivation |
| Date of first enrolment | 01/12/2005 |
| Date of final enrolment | 01/12/2007 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Erasmus Medical Centre
Rotterdam
3000 CA
Netherlands
3000 CA
Netherlands
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
