Outcomes after triceps branch to axillary nerve transfer assessed with dynamometer; a case series of 15 patients
| ISRCTN | ISRCTN69032529 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN69032529 |
| Secondary identifying numbers | 23/17428 |
- Submission date
- 16/05/2025
- Registration date
- 04/06/2025
- Last edited
- 04/06/2025
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Injury, Occupational Diseases, Poisoning
Plain English summary of protocol
Background and study aims
Nerve transfer with the triceps branch from the radial nerve to the axillary nerve is a widely used treatment method for isolated axillary nerve injury and has been used at Oslo University Hospital since 2011. The study aims to evaluate the clinical outcomes on a follow-up examination.
Who can participate?
All patients treated with this method for isolated axillary injury between 2011 to 2023.
What does the study involve?
The study involves clinical examination by an orthopaedic surgeon and a physiotherapist, with measurements of the movement in the shoulder, and the strength in the shoulder and elbow on both sides. The patients are also asked to fill out a questionnaire (Quick DASH).
What are the possible benefits and risks of participating?
The benefits of participation are mainly to provide information and increase knowledge about the procedure, and it does not involve any risks.
Where is the study run from?
Oslo University Hospital, Orthopaedic Department
When is the study starting and how long is it expected to run for?
March 2023 to October 2023
Who is funding the study?
Oslo University Hospital
Who is the main contact?
Hrønn Olafsdottir, orthopaedic surgeon, Unit for hand and microsurgery, hroola@ous-hf.no
Contact information
Public, Scientific
Oslo University Hospital, Sognsvannsveien 20
Oslo
0372
Norway
| Phone | +4723070000 |
|---|---|
| hroola@ous-hf.no |
Principal Investigator
Oslo University Hospital, Sognsvannsveien 20
Oslo
0372
Norway
| Phone | +4723070000 |
|---|---|
| rthorkil@ous-hf.no |
Study information
| Study design | Single-centre retrospective case series |
|---|---|
| Primary study design | Observational |
| Secondary study design | Case series |
| Study setting(s) | Hospital, Medical and other records |
| Study type | Treatment |
| Participant information sheet | Not available in web format, please use contact details to request a participant information sheet |
| Scientific title | Outcomes after triceps branch to axillary nerve transfer assessed with dynamometer; a case series of 15 patients |
| Study acronym | OTANT |
| Study objectives | To evaluate the clinical results in an Oslo University Hospital unit after treating isolated axillary nerve injury with a transfer of a triceps branch of the radial nerve to the axillary nerve. |
| Ethics approval(s) |
Approved 21/08/2023, Data Protection Officer, Oslo University Hospital (Postboks 4956 Nydalen, Oslo, 0424, Norway; +4723070000; personvern@oslo-universitetssykehus.no), ref: 23/17428 |
| Health condition(s) or problem(s) studied | Nerve transfer with triceps branch of radial nerve to the axillary nerve for isolated axillary nerve injury. |
| Intervention | Patients are identified via the hospital's record system, with patients treated between 2011 and 2023. They are invited to follow up for clinical examination with measurement of range of motion in the shoulder and strength with a dynamometer, and according to the British Medical Research Council (BMRC) scale. Donor morbidity will be evaluated with strength measurements in the same manner. Measurements will be compared to preoperative measurements. Special tests for deltoid dysfunction will be used on follow-up examination. |
| Intervention type | Procedure/Surgery |
| Primary outcome measure | Strength in the deltoid muscle was measured using a dynamometer, and according to the the British Medical Research Council (BMRC) scale at follow-up |
| Secondary outcome measures | 1. Range of motion in the shoulder measured using a goniometer pre- and postoperatively 2. Strength in the triceps muscle measured using a dynamometer and according to the British Medical Research Council (BMRC) scale at follow-up 3. Deltoid function measured using the Bertelli test, swallow tail test and deltoid extension lag test at follow-up 4. Patient-reported outcomes measured using QuickDASH questionnaire on follow-up |
| Overall study start date | 01/03/2023 |
| Completion date | 01/10/2023 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Mixed |
| Lower age limit | 17 Years |
| Upper age limit | 78 Years |
| Sex | Both |
| Target number of participants | 16 |
| Total final enrolment | 15 |
| Key inclusion criteria | All adult patients, treated with nerve transfer with triceps branch from radial nerve to axillary nerve, for isolated axillary nerve injury, from 2011-2023 in our unit, who accept participation with written consent. |
| Key exclusion criteria | 1. Children < 17 years 2. Non-acceptance of an invitation for follow-up |
| Date of first enrolment | 01/09/2023 |
| Date of final enrolment | 01/10/2023 |
Locations
Countries of recruitment
- Norway
Study participating centre
Oslo
0372
Norway
Sponsor information
Hospital/treatment centre
Postboks 4956 Nydalen
Oslo
0424
Norway
| Phone | +4723070000 |
|---|---|
| post@oslo-universitetssykehus.no | |
| Website | http://www.oslo-universitetssykehus.no/om-oss/english |
"ROR" |
https://ror.org/00j9c2840 |
Funders
Funder type
Hospital/treatment centre
Government organisation / Other non-profit organizations
- Alternative name(s)
- Oslo University Hospital, Oslo universitetssykehus, OUS
- Location
- Norway
Results and Publications
| Intention to publish date | 26/10/2023 |
|---|---|
| Individual participant data (IPD) Intention to share | Yes |
| IPD sharing plan summary | Published as a supplement to the results publication |
| Publication and dissemination plan | The results are planned to be presented at national and international conferences and in an international journal. |
| IPD sharing plan | The datasets generated and/or analysed during the current study will be published as a supplement to the results publication. |
Editorial Notes
04/06/2025: Study's existence confirmed by the Data Protection Officer, Oslo University Hospital.
