Preventing hospitalisation and early death from chronic heart failure in primary care: a randomised controlled trial of pharmacist led medication review
| ISRCTN | ISRCTN70118765 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN70118765 |
| Protocol serial number | 04/SO701/8 |
| Sponsor | Greater Glasgow Primary Care NHS Trust (UK) |
| Funder | NHS Glasgow Research and Development |
- Submission date
- 15/06/2006
- Registration date
- 06/07/2006
- Last edited
- 10/04/2012
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr Richard Lowrie
Scientific
Scientific
Primary Care Research and Development Directorate
Gartnavel Royal Hospital
1055 Great Western Road
Glasgow
Scotland
G12 OXH
United Kingdom
| Phone | +44 (0)141 211 3690 |
|---|---|
| Richard.lowrie@gartnavel.glacomen.scot.nhs.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial with cost effectiveness analysis |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | |
| Study objectives | Pharmacists in primary care can prevent hospitalisation and early death through medication review |
| Ethics approval(s) | 2004; Greater Glasgow Primary Care NHS Trust Local Research Ethics Committee |
| Health condition(s) or problem(s) studied | Chronic heart failure |
| Intervention | Practices in the control group, in common with intervention group, receive a complete disease register for patients with a diagnosis of chronic heart failure due to left ventricular systolic dysfunction. Control group practices do not receive any further pharmacist led support. Intervention practices receive pharmacist medication review for their patients with heart failure. |
| Intervention type | Other |
| Primary outcome measure(s) |
Death or heart failure hospitalisations |
| Key secondary outcome measure(s) |
Survival times until occurrence of first heart failure hospitalisation or death |
| Completion date | 01/06/2009 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 2400 |
| Key inclusion criteria | 1. Consenting practices 2. Patients with confirmed left ventricular systolic dysfunction (LSVD) providing written consent |
| Key exclusion criteria | 1. Non LVSD 2. Not chronic heart failure 3. Renal failure requiring dialysis 4. Patient under enhanced form of Primary Care |
| Date of first enrolment | 01/05/2004 |
| Date of final enrolment | 01/06/2009 |
Locations
Countries of recruitment
- United Kingdom
Study participating centre
Primary Care Research and Development Directorate
Scotland
G12 OXH
United Kingdom
G12 OXH
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 1. results | 01/02/2012 | Yes | No | |
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
