The Use of Proton Pump Inhibitors in General Practice
| ISRCTN | ISRCTN70358598 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN70358598 |
| Protocol serial number | RRCC704F R340166 |
| Sponsor | NHS R&D Regional Programme Register - Department of Health (UK) |
| Funder | NHS Executive Northern and Yorkshire (UK) |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 15/08/2011
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Digestive System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr A Raghunath
Scientific
Scientific
Marmaduke Health Centre
Hessle Road
Hull
HU3 3BH
United Kingdom
| Phone | +44 (0)1482 327 708 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | The aim of this study is three fold: to improve our understanding of the prescribing behaviour of GPs with regard to PPIs; to better understand the perceived benefits by patients and; to test the feasibility of an exercise designed to reduce their consumption. Objectives: 1. To ascertain the knowledge and attitudes of GPs and variations between GPs in prescribing PPIs, both when initiating therapy and for long-term maintenance. 2. To ascertain from patients on repeat PPI prescriptions the perceived benefits of treatment with PPIs, including symptom control and wider social benefits e.g. on lifestyle. 3. To devise and pilot for feasibility, and for evaluating sustainability, a strategy for switching a sample of patients on long term therapy to lower strengths of PPIs, with a view to advising a larger scale intervention study. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Digestive system diseases: Peptic ulcer disease |
| Intervention | Not provided at time of registration |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Proton Pump Inhibitors |
| Primary outcome measure(s) |
1. Better understanding of the prescribing behaviour of PPIs by General Practitioners. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 04/01/2002 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 10/01/1999 |
| Date of final enrolment | 04/01/2002 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Marmaduke Health Centre
Hull
HU3 3BH
United Kingdom
HU3 3BH
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/06/2005 | Yes | No |
