A randomised crossover study of citric acid cough challenge in healthy volunteers: Comparison of Mefar Dosimeter and Jaeger Aerosol Provocation System (APS)
| ISRCTN | ISRCTN71430262 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN71430262 |
| Protocol serial number | N0084118528 |
| Sponsor | Department of Health |
| Funder | The North and South Bank Research and Development Consortium (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 13/04/2018
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Miss Caroline Wright
Scientific
Scientific
Academic Department of Medicine
Castle Hill Hospital
Castle Road
Cottingham
HU16 5JQ
United Kingdom
| Phone | +44 (0)1482 875875 (4009/3782) |
|---|---|
| c.e.wright@hull.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled crossover group trial |
| Secondary study design | Randomised cross over trial |
| Study type | Participant information sheet |
| Scientific title | A randomised crossover study of citric acid cough challenge in healthy volunteers: Comparison of Mefar Dosimeter and Jaeger Aerosol Provocation System (APS) |
| Study objectives | Sub-study: To determine whether citric acid inhalation elevates tachykinin and nerve growth factor in sputum of males and females: is this gender related? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Respiratory: Cough challenge |
| Intervention | Comparison of Mefar Dosimeter and Jaeger Aerosol Provocation System (APS) |
| Intervention type | Other |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 26/04/2004 |
Eligibility
| Participant type(s) | Healthy volunteer |
|---|---|
| Age group | Not Specified |
| Sex | All |
| Target sample size at registration | 50 |
| Key inclusion criteria | 50 healthy volunteers |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 22/11/2002 |
| Date of final enrolment | 26/04/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Castle Hill Hospital
Cottingham
HU16 5JQ
United Kingdom
HU16 5JQ
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
13/04/2018: No publications found, verifying study status with principal investigator.
31/03/2016: No publications found, verifying study status with principal investigator.
