The effect of nerve sparing anterior resection on erectile function and the prospect of therapeutic early intervention
| ISRCTN | ISRCTN71503461 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN71503461 |
| Protocol serial number | N0264146222 |
| Sponsor | Department of Health |
| Funders | United Bristol Healthcare NHS Trust (UK), NHS R&D Support Funding |
- Submission date
- 30/09/2005
- Registration date
- 30/09/2005
- Last edited
- 09/03/2018
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Urological and Genital Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr T Whittlestone
Scientific
Scientific
C/O Research & Effectiveness Department
Level 1, The Old Building
Bristol Royal Infirmary
Marlborough Street
Bristol
BS2 8HW
United Kingdom
| Phone | +44 (0)117 928 3473 |
|---|---|
| r&eoffice@ubht.swest.nhs.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | The effect of nerve sparing anterior resection on erectile function and the prospect of therapeutic early intervention: a randomised controlled trial |
| Study objectives | The effect of a combination of nerve sparing resection and therapy with sildenafil on function following anterior resection. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Erectile dysfunction |
| Intervention | Patients undergoing anterior resection to be randomised between sildenafil versus placebo |
| Intervention type | Drug |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Sildenafil |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 25/12/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Male |
| Key inclusion criteria | Patients with rectal carcinoma |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 01/10/1999 |
| Date of final enrolment | 25/12/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Bristol Royal Infirmary
Bristol
BS2 8HW
United Kingdom
BS2 8HW
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
09/03/2018: No publications found, verifying study status with principal investigator.
11/02/2016: No publications found, verifying study status with principal investigator
