Manchester Asthma and Allergy Study
| ISRCTN | ISRCTN72673620 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN72673620 |
| Protocol serial number | N/A |
| Sponsor | Wythenshawe Hospital (UK) |
| Funders | Asthma UK (UK), Moulton Charitable Trust (UK) |
- Submission date
- 18/04/2006
- Registration date
- 05/05/2006
- Last edited
- 11/02/2019
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Adnan Custovic
Scientific
Scientific
North West Lung Research Centre
Wythenshawe Hospital
Southmoor Road
Manchester
M23 9LT
United Kingdom
| Phone | +44 (0)161 291 2494 |
|---|---|
| adnan.custovic@manchester.ac.uk |
Study information
| Primary study design | Observational |
|---|---|
| Study design | Prospective observational birth cohort study |
| Secondary study design | Cohort study |
| Study type | Participant information sheet |
| Scientific title | Manchester Asthma and Allergy Study |
| Study acronym | MAAS |
| Study objectives | Birth cohort study investigating the development of asthma and allergic disease |
| Ethics approval(s) | 1. Age 0 - 5 years follow up, ERP/94/032, approval received on 24/03/1994 2. Age 5 - 8 years follow up, SOU/00/258 and SOU/00/259, approval received on 20/12/2000 3. Age 8 - 11 years follow up, 03/SM/400, approval received on 05/12/2003 |
| Health condition(s) or problem(s) studied | Asthma and allergy |
| Intervention | This is a prospective, observational birth cohort study, which includes investigating environmental exposures, immune responses, behaviour or family functioning, genetic epidemiology, pulmonary physiology and clinical outcomes |
| Intervention type | Other |
| Primary outcome measure(s) |
1. Asthma at age 5, 8, 11 and 14 years |
| Key secondary outcome measure(s) |
1. Wheeze and eczema at age 1, 3, 5, 8, 11 and 14 years |
| Completion date | 01/06/2019 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Child |
| Sex | All |
| Target sample size at registration | 1250 |
| Key inclusion criteria | Children born at Wythenshawe Hospital, Manchester and Stepping Hill Hospital, Stockport between January 1996 and April 1998 |
| Key exclusion criteria | Premature birth <32 weeks gestation |
| Date of first enrolment | 01/09/1995 |
| Date of final enrolment | 01/06/2019 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Wythenshawe Hospital
Manchester
M23 9LT
United Kingdom
M23 9LT
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 15/06/2008 | Yes | No | |
| Results article | results | 01/06/2010 | Yes | No | |
| Results article | results | 01/12/2015 | Yes | No | |
| Results article | results | 15/10/2018 | Yes | No | |
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
11/02/2019: Publication reference added.
05/05/2016: Publication reference added.
