Blood transfusions for preterm infants and free radicals
| ISRCTN | ISRCTN72984863 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN72984863 |
| Protocol serial number | RHC18070 |
| Sponsor | NHS R&D Regional Programme Register - Department of Health (UK) |
| Funder | NHS Executive North West (UK) |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 03/12/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Neonatal Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Alan Weindling
Scientific
Scientific
Liverpool Women's Hospital
Neonatal Unit
Crown Street
Liverpool
L8 7SS
United Kingdom
| Phone | +44 (0)151 702 4093 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Does a blood transfusion in preterm infants cause free radical release? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Neonatal diseases |
| Intervention | Group 1 will have their need for blood transfusion monitored according to a standard protocol. Group 2 will have measurements of forearm fractional oxygen extraction (FOE) to guide their need for transfusions. |
| Intervention type | Other |
| Primary outcome measure(s) |
The primary outcome measure will be peak ODFR activity. |
| Key secondary outcome measure(s) |
A secondary outcome will be the number of days on the neonatal unit, retinopathy or prematurity, preventricular haemorrhage and periventricular leukomalacia and necrotising enterocolitis. |
| Completion date | 01/08/1999 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Neonate |
| Sex | Not Specified |
| Key inclusion criteria | Preterm infants |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/02/1998 |
| Date of final enrolment | 01/08/1999 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Liverpool Women's Hospital
Liverpool
L8 7SS
United Kingdom
L8 7SS
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/01/2002 | Yes | No |
