Propofol and remifentanil requirements after acute ethanol intake in clinical settings
| ISRCTN | ISRCTN73421343 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN73421343 |
| Secondary identifying numbers | N/A |
- Submission date
- 30/06/2005
- Registration date
- 08/07/2005
- Last edited
- 14/09/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Fotis Kanakoudis
Scientific
Scientific
Korytsas 14
Thessaloniki
55133
Greece
| Phone | +30 2310437531 |
|---|---|
| fkanak@otenet.gr |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study acronym | PRAECS |
| Study objectives | Null hypothesis:Patients receiving intravenous ethanol would not require smaller doses of propofol and remifentanil for induction and maintenance of anaesthesia. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Interaction of acute ethanol intravenous intake with propofol (general anesthetic) and remifentanil (opioid) |
| Intervention | Comparison of two groups (with different ethanol doses) versus control (no ethanol), regarding propofol and remifentanil requirements |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Propofol, remifentanil and acute ethanol |
| Primary outcome measure | Reduction of propofol and remifentanil requirements |
| Secondary outcome measures | Degree of reduction, side-effects |
| Overall study start date | 02/02/2004 |
| Completion date | 07/06/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target number of participants | 60 |
| Key inclusion criteria | Female surgical patients on general anesthesia |
| Key exclusion criteria | Alcoholic patients, patients in abstinence |
| Date of first enrolment | 02/02/2004 |
| Date of final enrolment | 07/06/2004 |
Locations
Countries of recruitment
- Greece
Study participating centre
Korytsas 14
Thessaloniki
55133
Greece
55133
Greece
Sponsor information
Theagenio Anticancer Hospital of Thessaloniki (Greece)
Hospital/treatment centre
Hospital/treatment centre
Al. Symeonidis 2
Thessaloniki
54007
Greece
| Phone | +30 2310898213 |
|---|---|
| amitragas@yahoo.com | |
| Website | http://www.theagenio.gr |
"ROR" |
https://ror.org/004hfxk38 |
Funders
Funder type
Hospital/treatment centre
Theagenio Anticancer Hospital of Thessaloniki (Greece)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
