Nephrectomy versus no nephrectomy for metastatic renal carcinoma
| ISRCTN | ISRCTN75184582 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN75184582 |
| Protocol serial number | RE03 |
| Sponsor | Medical Research Council (MRC) (UK) |
| Funder | Medical Research Council (MRC) (UK) |
- Submission date
- 28/02/2001
- Registration date
- 28/02/2001
- Last edited
- 26/02/2016
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Pat Cook
Scientific
Scientific
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | Nephrectomy versus no nephrectomy for metastatic renal carcinoma |
| Study objectives | To establish whether, in patients with metastatic renal carcinoma, nephrectomy has any advantage. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Renal Cancer |
| Intervention | 1. One group receives a nephrectomy 2. The other receives no nephrectomy |
| Intervention type | Other |
| Primary outcome measure(s) |
1. Time to progression |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/12/1998 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 120 |
| Key inclusion criteria | 1. Patient should have locally operable disease and should be fit enough for nephrectomy 2. A renal tumour with clinical or radiological evidence of metastases 3. No previous malignancy (except non-melanotic skin cancer or in situ carcinoma of the cervix) 4. Written informed consent of the patient |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/1995 |
| Date of final enrolment | 01/12/1998 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
MRC Clinical Trials Unit
London
NW1 2DA
United Kingdom
NW1 2DA
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
26/02/2016: No publications found, study status unverified.
