Randomised trial of extended antibiotic prophylaxis for fracture fixation and joint replacement: clinical benefits versus ecological risks

ISRCTN	ISRCTN75423827
DOI	https://doi.org/10.1186/ISRCTN75423827
Protocol serial number	G0100056
Sponsor	Medical Research Council (MRC) (UK)
Funder	Medical Research Council (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Prof Peter Davey
Scientific

Clinical Pharmacology & Therapeutics (MEMO Unit)
Department of Clinical Pharmacology
Ninewells Hospital
Dundee
DD1 9SY
United Kingdom

Phone	+44 (0)1382 632575
Email	p.g.davey@dundee.ac.uk

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study acronym	OPT
Study objectives	Not provided at time of registration
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Orthopaedics
Intervention	Not provided at time of registration Updated 29/05/2014: this trial did not start due to a lack of funding.
Intervention type	Other
Primary outcome measure(s)	Not provided at time of registration
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	01/05/2004
Reason abandoned (if study stopped)	Lack of funding/sponsorship

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Key inclusion criteria	Not provided at time of registration
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/05/1999
Date of final enrolment	01/05/2004

Clinical Pharmacology & Therapeutics (MEMO Unit)

Dundee
DD1 9SY
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan