Clinical medication review by a pharmacist of patients on repeat prescriptions in general practice

ISRCTN	ISRCTN77150103
DOI	https://doi.org/10.1186/ISRCTN77150103
Secondary identifying numbers	HTA 93/22/09

Submission date: 25/04/2003
Registration date: 25/04/2003
Last edited: 27/08/2009

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Other

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Arnold Zermansky
Scientific

School of Healthcare Studies
University of Leeds
Division of Academic Pharmacy Practice
Room 2.23 Baines Wing
PO Box 214
Leeds
LS2 9UT
United Kingdom

Phone	+44 (0)113 3431340
Email	zermansky@btinternet.com

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Not Specified
Scientific title
Study objectives	This randomised controlled clinical trial will examine whether a suitably experienced pharmacist can conduct effective clinical medication review of patients on repeat prescriptions. The study will compare this approach with a control group who will be part of the normal review mechanisms for repeat prescriptions. The pharmacist will be an experienced clinical pharmacist with the appropriate clinical and consultation skills. The objective is to assess whether clinical medication review by a pharmacist is a cost-effective method for improving the extent and quality of clinical control of repeat prescribing, compared with that achieved by the practices' normal procedures.
Ethics approval(s)	Not provided at time of registration.
Health condition(s) or problem(s) studied	Repeat prescriptions
Intervention	A total of 1200 patients from four practices will be randomised to the active or control group. Patients in the active group will be called for an appointment with the pharmacist at the surgery. The pharmacist will assess the continuing appropriateness of the medication regime and make appropriate recommendations (in conjunction with the GP). The control group will receive standard care.
Intervention type	Other
Primary outcome measure	The primary outcome was the number of repeat medication changes per patient over a 12-month period. The secondary outcome was the effect on the medication costs. The intervention group was compared with the control group to see whether a review had taken place, the numbers of medication changes, the numbers of repeat medications and the numbers of dosage times. The effects of the medication review clinics were considered in relation to practice consultations, outpatient consultations, hospital admissions and deaths from any cause. The number and nature of the pharmacist¿s interventions and recommendations were recorded, together with whether the recommendations were accepted by the GP.
Secondary outcome measures	Not provided at time of registration.
Overall study start date	01/03/1999
Completion date	31/03/2001

Eligibility

Participant type(s)	Patient
Age group	Not Specified
Sex	Both
Target number of participants	1200
Key inclusion criteria	Not provided at time of registration.
Key exclusion criteria	Not provided at time of registration.
Date of first enrolment	01/03/1999
Date of final enrolment	31/03/2001

Locations

Countries of recruitment

England
United Kingdom

Study participating centre

School of Healthcare Studies

Leeds
LS2 9UT
United Kingdom

Sponsor information

Department of Health (UK)
Government

Quarry House
Quarry Hill
Leeds
LS2 7UE
United Kingdom

Phone	+44 (0)1132 545 843
Email	Sheila.Greener@doh.gsi.gov.uk
Website	http://www.dh.gov.uk/en/index.htm
"ROR"	https://ror.org/03sbpja79

Funders

Funder type

Government

NIHR Health Technology Assessment Programme - HTA (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	08/12/2001		Yes	No