Asthma and air pollution
| ISRCTN | ISRCTN78763245 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN78763245 |
| ClinicalTrials.gov (NCT) | Nil known |
| Clinical Trials Information System (CTIS) | Nil known |
| Protocol serial number | 5F00E04015-0 |
| Sponsor | MetroHealth |
| Funder | U.S. Environmental Protection Agency |
- Submission date
- 04/02/2025
- Registration date
- 05/02/2025
- Last edited
- 05/02/2025
- Recruitment status
- Recruiting
- Overall study status
- Ongoing
- Condition category
- Respiratory
Plain English summary of protocol
Background and aims
Cooking on natural gas stoves is a major source of indoor air pollution, and this may be detrimental for people with asthma. This study will determine if changing gas stoves to electric stoves leads to an improvement in asthma control as measured by a symptom questionnaire.
Who can participate?
Households that use a gas stove for cooking, have at least one person with asthma, and are located in or near Cleveland, Ohio, United States of America.
What does the project involve?
This project team will change gas stoves to electric stoves at no charge to participating households. Changing the stove may take up to 1 week if a kitchen electrical upgrade is needed. Participants will be followed for 2-3 months after the stove change.
What are the possible benefits and risks of participating?
The potential benefit is an improvement in asthma control. There are no anticipated risks.
Where is the project run from?
The MetroHealth System (USA)
When is the project starting and how long is it expected to run for?
January 2024 to October 2027
Who is funding the project?
The United States Environmental Protection Agency (USA)
Who is the main contact?
Dr Ashwini Sehgal, sehgal@case.edu
Contact information
Public, Scientific, Principal investigator
2500 MetroHealth Drive
Rammelkamp Building Room 219
Cleveland
44109
United States of America
| Phone | +1 (0)2167787728 |
|---|---|
| sehgal@case.edu |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Interventional multi-site unblinded non-randomized single-arm study |
| Secondary study design | Non randomised study |
| Study type | Participant information sheet |
| Scientific title | Asthma and indoor air pollution |
| Study objectives | Replacing gas stoves with electric stoves will improve asthma control |
| Ethics approval(s) |
Approved 15/08/2024, MetroHealth IRB (2500 MetroHealth Drive, Cleveland, 44109, United States of America; +1 (0)216 778 7237; IRBOffice@metrohealth.org), ref: STUDY00000666 |
| Health condition(s) or problem(s) studied | Asthma |
| Intervention | This project team will change gas stoves to electric stoves at no charge to participating households. Changing the stove may take up to 1 week if a kitchen electrical upgrade is needed. Participants will be followed for 2-3 months after the stove change. |
| Intervention type | Other |
| Primary outcome measure(s) |
Asthma control assessed using the Asthma Control Questionnaire at baseline (defined as 1-4 weeks before stove change) and at follow-up (defined as 2-3 months after stove change) |
| Key secondary outcome measure(s) |
There are no secondary outcome measures |
| Completion date | 31/10/2027 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | All |
| Sex | All |
| Target sample size at registration | 265 |
| Key inclusion criteria | 1. At least one person in the household has self-reported asthma 2. Person with asthma has an asthma control questionnaire score of 1.5 or higher 3. Household uses a gas stove for cooking and is interested in changing to an electric stove 4. Household located in or near Cleveland, Ohio, United States of America |
| Key exclusion criteria | Does not meet the inclusion criteria |
| Date of first enrolment | 10/02/2025 |
| Date of final enrolment | 30/09/2027 |
Locations
Countries of recruitment
- United States of America
Study participating centre
Cleveland
44109
United States of America
Results and Publications
| Individual participant data (IPD) Intention to share | Yes |
|---|---|
| IPD sharing plan summary | Available on request |
| IPD sharing plan | The datasets generated during and/or analyzed will be available upon request from Dr Ashwini Sehgal (sehgal@case.edu) |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
05/02/2025: Study's existence confirmed by MetroHealth IRB.
