Thymectomy trial in non-thymomatous myasthenia gravis patients receiving immunosuppressive therapy
| ISRCTN | ISRCTN78813854 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN78813854 |
| Protocol serial number | G0100023 |
| Sponsor | Sponsor not defined - application in progress |
| Funder | Not provided at time of registration |
- Submission date
- 18/05/2001
- Registration date
- 18/05/2001
- Last edited
- 04/10/2018
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Nutritional, Metabolic, Endocrine
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr John Newsom-Davis
Scientific
Scientific
Department of Clinical Neurology
University of Oxford
Radcliffe Infirmary
Oxford
OX2 6HE
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | Thymectomy trial in non-thymomatous myasthenia gravis patients receiving immunosuppressive therapy |
| Study acronym | TxMG trial |
| Study objectives | To determine whether extended trans-sternal thymectomy reduces corticosteroid requirements for patients with generalised acetylcholine receptor (AChR) antibody-positive non-thymomatous myasthenia gravis (MG). |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Endocrinology |
| Intervention | Not provided at time of registration |
| Intervention type | Other |
| Primary outcome measure(s) | Not provided at time of registration |
| Key secondary outcome measure(s) | Not provided at time of registration |
| Completion date | 01/06/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/06/2005 |
| Date of final enrolment | 01/06/2007 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
University of Oxford
Oxford
OX2 6HE
United Kingdom
OX2 6HE
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 11/08/2016 | Yes | No | |
| Protocol article | protocol | 01/04/2008 | Yes | No | |
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
04/10/2018: Publication reference added.
