Impact of adrenal gland volume on outcome of septic shock patients
| ISRCTN | ISRCTN79359473 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN79359473 |
| Protocol serial number | None |
| Sponsor | University Teaching Hospital of Montpellier (CHU de Montpellier) (France) |
| Funder | Saint Eloi Hospital (France) - Intensive Care and Transplantation Unit (Unité de Réanimation et Transplantation) |
- Submission date
- 21/03/2010
- Registration date
- 27/04/2010
- Last edited
- 05/10/2011
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Nutritional, Metabolic, Endocrine
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Samir Jaber
Scientific
Scientific
Service d'Anesthésie-Réanimation B
Unité de Réanimation et Transplantation
Hôpital Saint Eloi
80 Avenue Augustin Fliche
Montpellier
34295
France
Study information
| Primary study design | Observational |
|---|---|
| Study design | Single centre observational study |
| Secondary study design | Cohort study |
| Study type | Participant information sheet |
| Scientific title | Impact of adrenal gland volume measured non invasively with a CT scan on outcome of septic shock patients admitted in the Intensive Care Unit: A single centre, observational trial |
| Study objectives | 1. To assess the impact of adrenal gland volume measured non invasively with a CT scan on outcome of septic shock patients admitted in the Intensive Care Unit. 2. To compare adrenal gland volume between septic and non septic patients. 3. To examine the relationship between adrenal gland volume and adrenal gland function assessed by hormonal tests. |
| Ethics approval(s) | Local ethics committee approval |
| Health condition(s) or problem(s) studied | Septic Shock; Adrenal gland; Critical Illness related Corticoid Insuffisency |
| Intervention | Observational trial of patients receiving routine care with an abdominal CT scan |
| Intervention type | Other |
| Primary outcome measure(s) |
Mortality at day 28 |
| Key secondary outcome measure(s) |
1. ICU length of mechanical ventilation |
| Completion date | 01/05/2010 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | All |
| Target sample size at registration | 150 |
| Key inclusion criteria | 1. Septic shock patients: septic shock defined using the Bone guidelines (Bone et al, Chest 1992;101(6):1644-55) admitted in the ICU and explored both with a short cosyntropin test and an abdominal CT scan 2. Non septic patients admitted to Intensive Care Unit with explored abdominal CT scan 3. Outpatients clinic patients explored for abdominal pain with a normal CT scan 4. Male and female, age ≥ 18 |
| Key exclusion criteria | 1. Chronic steroid consumption 2. Adrenal gland specific pathology prior to admission |
| Date of first enrolment | 01/03/2007 |
| Date of final enrolment | 01/05/2010 |
Locations
Countries of recruitment
- France
Study participating centre
Service d'Anesthésie-Réanimation B
Montpellier
34295
France
34295
France
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/08/2011 | Yes | No | |
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
