Clinical benefits of additional resistance-type exercise during an endurance-type exercise intervention in coronary artery disease patients
| ISRCTN | ISRCTN81212339 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN81212339 |
| Secondary identifying numbers | 07.48/cardio07.081 |
- Submission date
- 14/01/2010
- Registration date
- 09/02/2010
- Last edited
- 09/02/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Dominique Hansen
Scientific
Scientific
Jessa Hospital
Stadsomvaart 11
Hasselt
3500
Belgium
Study information
| Study design | Prospective randomised clinical trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Quality of life |
| Participant information sheet | Not available in web format, please use the contact details below to request a patient information sheet |
| Scientific title | Clinical benefits of additional resistance-type exercise during an endurance-type exercise intervention in coronary artery disease patients: a randomised controlled trial |
| Study acronym | STIMCARE |
| Study objectives | We hypothesise that by adding resistance-type exercise during an endurance-type exercise intervention, significantly greater clinical benefits are achieved in coronary artery disease patients. |
| Ethics approval(s) | Medical Ethical Committee of Jessa Hospital approved on the 29th January 2007 (ref: 07.48/cardio07.081) |
| Health condition(s) or problem(s) studied | Coronary artery disease |
| Intervention | All subjects exercised under close supervision of experienced physiotherapists three days per week for a total duration of six weeks in the cardiac rehabilitation centre of the hospital. Exercise training intensity was determined by baseline VO2 peak assessment: subjects exercised at a heart rate corresponding to 65% of baseline VO2 peak, for 40 minutes each exercise training session (17 minutes cycling, 13 minutes walking, 10 minutes arm cranking). Subjects were randomly (by coin) assigned to an endurance-training group, or combined endurance and strength-training group. |
| Intervention type | Other |
| Primary outcome measure | 1. Maximal exercise capacity 2. Sub-maximal exercise capacity 3. Muscle strength 4. Blood plasma lipid profile and glycaemic control 5. Habitual activity level These measurements were executed at entry of rehabilitation, and after 7 weeks of rehabilitation. |
| Secondary outcome measures | 1. Blood endothelial progenitor cell 2. Cytokine content These measurements were executed at entry of rehabilitation, and after 7 weeks of rehabilitation. |
| Overall study start date | 01/02/2008 |
| Completion date | 01/03/2010 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 60 |
| Key inclusion criteria | 60 coronary artery disease (CAD) patients (aged between 45 - 80 years, either sex) agreed to participate in this study. |
| Key exclusion criteria | 1. Complicated hospitalisation (renal failure, sepsis) 2. Delayed and/or complicated sternum healing 3. Hypertension (greater than 150 mmHg systolic blood pressure at rest and/or greater than 250 mmHg systolic blood pressure during exercise) 4. Presence of pulmonary and renal co-morbidity 5. Peripheral artery disease 6. Orthopaedic limitations 7. Subjects presenting myocardial ischaemia and/or severe ventricular arrhythmias during baseline exercise testing |
| Date of first enrolment | 01/02/2008 |
| Date of final enrolment | 01/03/2010 |
Locations
Countries of recruitment
- Belgium
Study participating centre
Jessa Hospital
Hasselt
3500
Belgium
3500
Belgium
Sponsor information
Heart Centre Hasselt vzw (Belgium)
Hospital/treatment centre
Hospital/treatment centre
Begeveldstraat
Bilzen
3740
Belgium
| Website | http://www.jessazh.be/ |
|---|---|
"ROR" |
https://ror.org/03tw90478 |
Funders
Funder type
Hospital/treatment centre
Heart Centre Hasselt vzw (Belgium)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
