Bolus thrombolysis in cardiac arrest: a randomised controlled trial
| ISRCTN | ISRCTN81334888 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN81334888 |
| Protocol serial number | N0280113809 |
| Sponsor | Department of Health (UK) |
| Funder | Wirral Hospitals NHS Trust (UK) |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 31/08/2010
- Recruitment status
- Stopped
- Overall study status
- Stopped
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Jane McVicar
Scientific
Scientific
A&E
Arrowe Park Hospital
Arrowe Park Road
Upton
Wirral
CH49 5PE
United Kingdom
| Phone | +44 (0)151 230 0640 |
|---|---|
| beluga.whale@btopenworld.com |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Does bolus thrombolysis improve survival? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular: Bolus thrombolysis |
| Intervention | Single bolus dose tenecteplase or placebo given after first iv adrenaline on arrival in Accident and Emergency. Questionnaire to be completed by staff and collected by researcher. Added 30/08/10: trials was discontinued as of June 2006 |
| Intervention type | Other |
| Primary outcome measure(s) |
Survival (numbers), adverse events/bleeding, neurological status of survivors. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 30/09/2005 |
| Reason abandoned (if study stopped) | Lack of funding/sponsorship |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | 1. All patients attending Accident and Emergency with out-of-hospital cardiac arrest 2. Aged 16-79 years old |
| Key exclusion criteria | 1. Inappropriate for resuscitation 2. Late pregnancy |
| Date of first enrolment | 01/09/2002 |
| Date of final enrolment | 30/09/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
A&E
Wirral
CH49 5PE
United Kingdom
CH49 5PE
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
