Compression Only CardioPulmonary Resuscitation in telephone-assisted bystanders (COCPR III)

ISRCTN	ISRCTN82728488
DOI	https://doi.org/10.1186/ISRCTN82728488
Protocol serial number	V1.0
Sponsor	Medical University of Vienna (Austria)
Funder	Laerdal (Austria)

Submission date: 01/05/2014
Registration date: 14/05/2014
Last edited: 14/08/2019

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Background and study aims
High quality chest compressions are vital for survival after a cardiac arrest. Therefore bystanders are encouraged to act decisively in presence of a cardiac arrest victim. Telephone instructions are given by the emergency services responding to emergency calls. Unfortunately the quality of chest compression is usually inefficient because bystanders are often not trained. The aim of this study is to improve the quality of chest compression by comparing different instruction techniques.

Who can participate?
Your participation is voluntary. You need at least 18, give an informed consent and your blood pressure should be less than 150 mm Hg before the study starts.

What does the study involve?
Participants are randomly allocated to one of three groups: standard instructions given by emergency services over the phone, metronome over the phone, voice metronome over the phone.
If you take part two questionnaires are requested. The first one is about demographic data (age, smoking habits etc). The second questionnaire evaluates your physical fitness. Afterwards, you are requested to perform a skill test evaluating fine motor skills (you need to put pegs into holes with your non-dominant hand). Before the study starts your blood pressure and your heart rate are measured.
The main study is a simulated 10-minute cardiopulmonary resuscitation on a manikin (as for a cardiac arrest victim at home). Over the telephone, emergency services will give you instructions on how to resuscitate the victim (chest compression only resuscitation). During the resuscitation we will ask you for your subjective perceived exertion. After you have finished the simulated resuscitation scenario we will measure your heart rate and your blood pressure again. Also, you are requested to repeat the skill test.

What are the possible benefits and risks of participating?
There are no anticipated risks. The benefit will be improved basic life support skills.

Where is this study run from?
This study is organised by the Department of Emergency Medicine of the Medical University of Vienna. The study venue is a large shopping hall. Verbal instructions are given by a member of emergency services located in an emergency dispatch centre.

When is the study starting and how long is it expected to run for?
June 2014. Your participation will take only 15 minutes.

Who is funding the study?
The study is being funded by Laerdal Austria which will provide the Laerdal manikin.

Who is the main contact?
Dr. Raphael van Tulder
raphael.van-tulder@meduniwien.ac.at

Contact information

Dr Raphael van Tulder
Scientific

Department of Emergency Medicine
Medical University of Vienna
Waehringerguertel 18-20
Vienna
1090
Austria

Phone	+43 (0) 1 40400 1964
Email	raphael.van-tulder@meduniwien.ac.at

Study information

Primary study design	Interventional
Study design	Prospective randomized investigator-blinded parallel-group simulation trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	Effect of a (voice) metronome on chest compression depth and compression rate in telephone-assisted cardiopulmonary resuscitation: a randomized three-armed simulation study
Study acronym	COCPR III
Study objectives	Compression depth can be improved by a continuously repeated voice metronome sequence: 'deep-deep-deep-deeper'.
Ethics approval(s)	Medical University of Vienna Ethics Committee, 21/05/2013, 1318/2013
Health condition(s) or problem(s) studied	Cardiopulmonary resuscitation
Intervention	The scenario is planned as an out of hospital, telephone assisted, bystander CPR. Substantial information about circumstances (at home, compression only, telephone assisted bystander CPR) is given prior to participation. Outcome is blinded to the participants. After informed consent, participants are guided to a simulation room where the manikin is prepared. Only minimal study staff will have access to the scenario room to avoid distractions. The study staff's assignment is documentation of parameters and not to be involved in bystander CPR. Participants will be staffed with a telephone to call the Emergency Dispatch Centre (EDC). In the EDC, a professional emergency dispatcher will be providing verbal prompts via telephone to the bystander. Every participant will perform closed-chest compression for 10 minutes on a slightly modified Resusci Anne® Manikin (Laerdal, Norway) without giving rescue breaths. Participants will be randomized to one of three groups: 1. Standard instructions will be given by the emergency medical dispatcher via telephone following the AMPDS protocol V12.0 provided by the IAED. 2. A metronome with a rate of 110 bpm will be transmitted via telephone. 3. A voice metronome will continuously prompt: 'deep-deep-deep-deeper!' at a rate of 100 beats per minute. Data will be collected using the Laerdal® PC Skill-Reporting System - a software used with the adult size Laerdal® Resusci® Anne SkillReporterTM manikin to collect the subjects' CPR performance.
Intervention type	Other
Primary outcome measure(s)	Chest compression depth, measured continously via the pc skillmeter software of the Resusci® Anne skillmeter
Key secondary outcome measure(s)	1. Quality of ECC defined as number of percent of adequately achieved compression depth, continously assesed via skillmeter pc 2. Time to measurable decay in chest compression depth, continously assesed via skillmeter pc 3. Frequency of chest compression, continously assesed via skillmeter pc 4. Correct recoiling of the manikin's chest, continously assesed via skillmeter pc 5. Heart rate/systolic blood pressure ratio reflecting physical strain, measured before and immediately after chest compression 6. BORG rate of perceived exertion measured at 2nd, 4th, 6th and 10th minute of chest compressions 7. Systolic and diastolic blood pressure, measured before and immediately after chest compression 8. Nine Hole Peg Test, measured before and immediately after chest compression
Completion date	10/06/2014

Eligibility

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	All
Target sample size at registration	24
Total final enrolment	36
Key inclusion criteria	1. Voluntary participants 2. Informed consent 3. Age over 18 years 4. Blood pressure less than 160 mmHg (systolic) before starting CPR simulation
Key exclusion criteria	1. Healthcare professionals 2. Basic Life Support course performed within the last 6 months 3. Pregnancy 4. Blood pressure over 150 mm Hg (systolic) before starting CPR simulation
Date of first enrolment	10/06/2014
Date of final enrolment	10/06/2014

Locations

Countries of recruitment

Austria

Study participating centre

Department of Emergency Medicine

Vienna
1090
Austria

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/11/2015	21/01/2019	Yes	No
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes

Editorial Notes

14/08/2019: The final enrolment number has been added from the reference.
21/01/2019: Publication reference added