The relationship between anaesthetic induction agent type or dose and clinical outcome in patients with depression undergoing electroconvulsive therapy (ECT)
| ISRCTN | ISRCTN83454584 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN83454584 |
| Protocol serial number | N0084132839 |
| Sponsor | Department of Health |
| Funder | The North and South Bank Research and Development Consortium (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 05/12/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Godfrey Bwalya
Scientific
Scientific
Miranda House
Gladstone Street
Hull
HU3 2RT
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | The relationship between anaesthetic induction agent type or dose and clinical outcome in patients with depression undergoing electroconvulsive therapy (ECT) |
| Study objectives | Is there a relationship between the effect of a dose or type of anaesthetic induction agent on seizure duration and clinical outcome in patients undergoing electrical convulsive therapy for depression? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Mental and Behavioural Disorders: Depression |
| Intervention | Randomised 40 subjects to each of the four anaesthetic induction agent groups. Pre-ECT Hamilton Depression Rating Scale (HAM-D) score. Six sessions of ECT, observed motor seizure during, electroencephalogram (EEG) seizure duration in seconds. Post ECT HAM-D score done 1-2 days following ECT treatment. |
| Intervention type | Procedure/Surgery |
| Primary outcome measure(s) |
Hamilton Depression Scale scores and data collection forms. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/12/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 160 |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/03/2003 |
| Date of final enrolment | 01/12/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Miranda House
Hull
HU3 2RT
United Kingdom
HU3 2RT
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
