Carbon monoxide and Compound A measurements with desflurane and sevoflurane anaesthesia in humans: an observational study
| ISRCTN | ISRCTN84188372 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN84188372 |
| Protocol serial number | N/A |
| Sponsor | Vrije University Medical Centre (VUMC) (The Netherlands) |
| Funder | Vrije University Medical Centre (VUMC) (The Netherlands) |
- Submission date
- 27/06/2007
- Registration date
- 27/06/2007
- Last edited
- 06/08/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr C. Keijzer
Scientific
Scientific
Netherlands Cancer Institute (NKI)
Plesmanlaan 121
Amsterdam
1066 CX
Netherlands
| Phone | +31 (0)20 512 9111 |
|---|---|
| c.keijzer@nki.nl |
Study information
| Primary study design | Observational |
|---|---|
| Study design | Observational, case-control study |
| Secondary study design | Case-control study |
| Scientific title | Carbon monoxide and Compound A measurements with desflurane and sevoflurane anaesthesia in humans: an observational study |
| Study objectives | The purpose of this study is to register the average Carbon monoxide (CO) concentrations in forty patients receiving desflurane or sevoflurane anaesthesia after implementation of a safety protocol to prevent desiccation of the strong base containing absorbent Drägersorb 800 Plus®. |
| Ethics approval(s) | Ethics approval received from the local medical ethics committee |
| Health condition(s) or problem(s) studied | Anaesthesia |
| Intervention | Desflurane or sevoflurane anaesthesia. |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Desflurane, sevoflurane |
| Primary outcome measure(s) |
Amount of carbon monoxide or compound A produced. |
| Key secondary outcome measure(s) |
No secondary outcome measures |
| Completion date | 01/10/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target sample size at registration | 40 |
| Total final enrolment | 40 |
| Key inclusion criteria | 1. Non-smoking patients 2. American Society of Anaesthesiologists physical status class 1 to 3 3. Scheduled for a surgical procedure that would last at least ninety minutes |
| Key exclusion criteria | 1. Younger than 18 years of age 2. Suffering from terminal renal failure |
| Date of first enrolment | 01/08/2005 |
| Date of final enrolment | 01/10/2006 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Netherlands Cancer Institute (NKI)
Amsterdam
1066 CX
Netherlands
1066 CX
Netherlands
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 08/05/2008 | 06/08/2021 | Yes | No |
Editorial Notes
06/08/2021: Publication reference and total final enrolment added.
