Single centre randomised controlled trial (RCT) of a chest pain observation unit versus routine care

ISRCTN	ISRCTN85078221
DOI	https://doi.org/10.1186/ISRCTN85078221
Protocol serial number	RBP 00XX4
Sponsor	NHS R&D Regional Programme Register - Department of Health (UK)
Funder	NHS Executive Trent (UK)

Submission date: 23/01/2004
Registration date: 23/01/2004
Last edited: 22/02/2008

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Steve Goodacre
Scientific

Medical Care Research Unit
School of Health and Related Research
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA
United Kingdom

Phone	+44 (0)114 222 0842
Email	s.goodacre@sheffield.ac.uk

Study information

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study acronym	ESCAPE
Study objectives	To measure the effect of availability of a Chest Pain Observation Unit upon outcome of patients attending with chest pain and measure the cost-effectiveness of a Chest Pain Observation Unit in a UK hospital.
Ethics approval(s)	The study protocol was approved by the North Sheffield Research Ethics Committee.
Health condition(s) or problem(s) studied	Cardiovascular diseases: Heart disease
Intervention	1. Chest pain observation unit 2. Standard care
Intervention type	Other
Primary outcome measure(s)	Proportion of cases of myocardial infarction (MI) inappropriately sent home by 72 hours after attendance.
Key secondary outcome measure(s)	1. Quality of life, health and patients satisfaction at one month 2. Hospital reattendance rates and adverse cardiac event rates at one year and hospital resource usage over one year 3. Quality of life questionnaire (36-item short form health survey [SF-36]) anxiety/depression scales (Hospital anxiety and depression scale [HADS]) and health utility scale (EQ-5D)
Completion date	31/01/2002

Eligibility

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target sample size at registration	900
Key inclusion criteria	900 patients attending accident and emergency with a primary complaint of chest pain between 7.00am and 7.00pm.
Key exclusion criteria	1. Electrocardiogram (ECG) abnormality 2. Unstable angina 3. Co-morbidity 4. Less than 25 years 5. Unable to consent
Date of first enrolment	05/02/2001
Date of final enrolment	31/01/2002

Locations

Countries of recruitment

United Kingdom
England

Study participating centre

Medical Care Research Unit

Sheffield
S1 4DA
United Kingdom

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	Results	29/07/2004		Yes	No